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Survival After Declining Pediatric Tracheostomy Placement
Palmila Liu1, Rebecca L Brooks2, Candice H Bailey2
1Department of Otolaryngology - Head & Neck Surgery, University of Texas Southwestern Medical Center, Dallas, Texas, USA.
Insights
Caregivers declining tracheostomy for critically ill children resulted in significantly higher mortality rates. Factors like younger age, sepsis, and intubation influenced survival outcomes in these pediatric patients.
Area of Science:
- Pediatric critical care medicine
- Surgical outcomes in children
- Patient and family decision-making in healthcare
Background:
- Tracheostomy placement is a critical decision for critically ill children requiring prolonged mechanical ventilation.
- Caregiver preferences significantly influence treatment pathways, including the decision for tracheostomy.
- Understanding survival implications of declining tracheostomy is vital for informed consent and care planning.
Purpose of the Study:
- To evaluate the survival rates of critically ill children whose caregivers declined tracheostomy placement.
- To identify factors associated with mortality in pediatric patients who did not undergo tracheostomy.
- To provide data to aid families in the complex decision-making process regarding tracheostomy.
Main Methods:
- A retrospective cohort study included children under 18 years who had a pre-tracheostomy consultation.
- Data on comorbidities and mortality were compared between children whose caregivers declined tracheostomy versus those who agreed.
- Statistical analyses, including odds ratios and hazard ratios, were used to assess mortality risk.
Main Results:
- Mortality was substantially higher (52%) in children whose caregivers declined tracheostomy compared to those who agreed (21%).
- Factors associated with increased mortality in the declining group included sepsis and intubation.
- Median survival after declining tracheostomy was 31.9 months, with declining placement linked to a fourfold increased mortality risk.
Conclusions:
- Declining tracheostomy placement is associated with a significantly increased risk of mortality in critically ill children.
- Specific clinical factors such as sepsis and intubation are critical predictors of poor outcomes in this population.
- The findings underscore the importance of comprehensive counseling for families facing decisions about pediatric tracheostomy.
Objective:
To determine survival among critically ill children when caregivers decline tracheostomy placement.
Study Design:
Retrospective cohort.
Methods:
All children (<18 years) obtaining a pre-tracheostomy consultation at a tertiary children's hospital between 2016 and 2021 were included. Comorbidities and mortality were compared between children of caregivers that declined or agreed to tracheostomy.
Results:
Tracheostomy was declined for 58 children but was placed for 203 children. After consultation, mortality was 52% (30/58) when declining and 21% (42/230) when agreeing to tracheostomy (p < 0.001) at a mean of 10.7 months (standard deviation [SD]: 16) and 18.1 months (SD: 17.1), respectively (p = 0.07). For those declining, 31% (18/58) died during the hospitalization within a mean of 1.2 months (SD: 1.4) while 21% (12/58) died at a mean of 23.6 months (SD: 17.5) after discharge. Among children of caregivers declining tracheostomy, older age (odds ratio [OR]: 0.85, 95% confidence interval [CI]: 0.74-0.97, p = 0.01) and chronic lung disease (OR: 0.18, 95% CI: 0.04-0.82, P = .03) were associated with lower odds of mortality but sepsis (OR: 9.62, 95% CI: 1.161-57.43, p = 0.01) and intubation (OR: 4.98, 95% CI: 1.24-20.08, p = 0.02) were associated with higher odds of mortality. Median survival after declining tracheostomy was 31.9 months (interquartile range [IQR]: 2.0-50.7) and declining placement was associated with increased mortality risk (hazard ratio [HR]: 4.04, 95% CI: 2.49-6.55, p < 0.001).
Conclusion:
When caregivers declined tracheostomy placement, less than half of critically ill children in this cohort survived with younger age, sepsis, and intubation associated with higher mortality. This information offers valuable insight for families weighing decisions pertaining to pediatric tracheostomy placement.
Level Of Evidence:
3 Laryngoscope, 133:3602-3607, 2023.
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