Related Experiment Video
Updated: Aug 1, 2025

A Syngeneic Mouse Model of Metastatic Renal Cell Carcinoma for Quantitative and Longitudinal Assessment of Preclinical Therapies
Published on: April 12, 2017
Pediatric renal tumor epidemiology: Global perspectives, progress, and challenges
Jaime Libes1, Janna Hol2, Joaquim Caetano de Aguirre Neto3
1Department of Pediatrics, University of Illinois College of Medicine, Peoria, Illinois, USA.
Pediatric renal tumors, primarily Wilms tumor, are a significant childhood cancer. Global epidemiology studies improve understanding, risk factor identification, and tailored therapies, enhancing survival rates for affected children.
Area of Science:
- Pediatric oncology
- Cancer epidemiology
- Global health
Background:
- Pediatric renal tumors represent 3%-11% of childhood cancers.
- Wilms tumor (nephroblastoma) is the most common type.
- Epidemiology is crucial for cancer prevention, control, and risk factor identification.
Conclusions:
- Global epidemiological research has significantly advanced pediatric renal tumor understanding and treatment.
- Despite progress, challenges persist, and equitable outcomes are not universal.
- Further research is needed to address knowledge gaps and disparities in care, particularly in resource-limited settings.
Related Concept Videos
Chronic Kidney Disease I: Introduction
Kidney Transplant II: Surgical Procedure
Acute Kidney Injury IV: Diagnostic Studies and Prevention
Renal Drug Clearance: Overview
Renal clearance can be calculated using different methods. One approach is to divide the urinary drug excretion rate by the plasma drug concentration. This method directly measures renal clearance, indicating the kidneys' efficiency in...
Kidney Transplant I: Introduction

