Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Concept Videos

Angle Closure Glaucoma: Treatment01:28

Angle Closure Glaucoma: Treatment

587
Angle-closure glaucoma, or closed-angle glaucoma, is an eye condition where the iris bulges out and blocks the iridocorneal angle, resulting in a buildup of aqueous humor and increased intraocular pressure. Immediate medical attention is necessary due to the sudden onset of symptoms. The treatment for angle-closure glaucoma includes short-term and long-term approaches. Short-term treatment involves using eye drops like pilocarpine to lower intraocular pressure by increasing aqueous humor...
587
Open Angle Glaucoma: Treatment01:27

Open Angle Glaucoma: Treatment

504
In open-angle glaucoma, the iridocorneal angle remains open, but the trabecular meshwork becomes stiff, slowing down the outflow of aqueous humor. This causes a buildup of aqueous humor in the anterior chamber, leading to a sudden increase in intraocular pressure. The treatment for open-angle glaucoma focuses on reducing the elevated intraocular pressure by either decreasing the secretion of aqueous humor or increasing its outflow.
Drugs such as carbonic anhydrase inhibitors, α2- and...
504

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by
Same author

Dehydration and Rehydration Behavior of Ultra-High-Fluence Extracorporeal Cross-Linked Corneal Allogenic Intrastromal Ring Segments (ECO-CAIRS).

Journal of cataract and refractive surgery·2026
Same author

Risk behaviors for infectious Keratitis among contact lens wearers in Switzerland: an analysis by contact lens type.

Journal of optometry·2026
Same author

Second-Generation ELZA-sub400 Protocol: Individualized High-Fluence Cross-Linking for Ultra-Thin Keratoconus Corneas.

American journal of ophthalmology·2026
Same author

Cutting-edge cross-linking biomaterials advancing ophthalmic therapeutics.

Progress in retinal and eye research·2026
Same author

Comment on "Impact of Simultaneous Topography-Guided PRK on Corneal Haze after Cross-Linking for Keratoconus: A Quantitative Densitometry Analysis".

Cornea·2026
Same author

Integration of Mechanical Testing, In Vivo Optical Coherence Elastography and Personalized Finite Element Modeling to Predict Geometrical Outcomes of Corneal Cross-Linking.

Annals of biomedical engineering·2026

Related Experiment Video

Updated: Aug 1, 2025

Three Different Protocols of Corneal Collagen Crosslinking in Keratoconus: Conventional, Accelerated and Iontophoresis
07:29

Three Different Protocols of Corneal Collagen Crosslinking in Keratoconus: Conventional, Accelerated and Iontophoresis

Published on: November 12, 2015

20.0K

Expanding indications for corneal cross-linking.

Farhad Hafezi1,2,3,4,5, Emilio A Torres-Netto1,2,6, Mark Hillen1

  • 1ELZA Institute, Dietikon/Zurich.

Current Opinion in Ophthalmology
|April 25, 2023
PubMed
Summary

Corneal cross-linking (CXL) has advanced with new technologies for treating thin corneas and infectious keratitis. These innovations expand CXL applications beyond keratoconus to refractive surgery and vision rehabilitation.

More Related Videos

Second Harmonic Generation Signals in Rabbit Sclera As a Tool for Evaluation of Therapeutic Tissue Cross-linking TXL for Myopia
12:25

Second Harmonic Generation Signals in Rabbit Sclera As a Tool for Evaluation of Therapeutic Tissue Cross-linking TXL for Myopia

Published on: January 6, 2018

7.8K
Scleral Cross-linking Using Riboflavin and Ultraviolet-A Radiation for Prevention of Axial Myopia in a Rabbit Model
05:56

Scleral Cross-linking Using Riboflavin and Ultraviolet-A Radiation for Prevention of Axial Myopia in a Rabbit Model

Published on: April 3, 2016

9.0K

Related Experiment Videos

Last Updated: Aug 1, 2025

Three Different Protocols of Corneal Collagen Crosslinking in Keratoconus: Conventional, Accelerated and Iontophoresis
07:29

Three Different Protocols of Corneal Collagen Crosslinking in Keratoconus: Conventional, Accelerated and Iontophoresis

Published on: November 12, 2015

20.0K
Second Harmonic Generation Signals in Rabbit Sclera As a Tool for Evaluation of Therapeutic Tissue Cross-linking TXL for Myopia
12:25

Second Harmonic Generation Signals in Rabbit Sclera As a Tool for Evaluation of Therapeutic Tissue Cross-linking TXL for Myopia

Published on: January 6, 2018

7.8K
Scleral Cross-linking Using Riboflavin and Ultraviolet-A Radiation for Prevention of Axial Myopia in a Rabbit Model
05:56

Scleral Cross-linking Using Riboflavin and Ultraviolet-A Radiation for Prevention of Axial Myopia in a Rabbit Model

Published on: April 3, 2016

9.0K

Area of Science:

  • Ophthalmology
  • Biomedical Engineering

Background:

  • Corneal cross-linking (CXL) is evolving beyond its initial application for keratoconus.
  • Recent advancements focus on improving safety, efficacy, and expanding indications for CXL procedures.

Approach:

  • Review of recent technological advancements in CXL, including enhanced ultraviolet (UV) light sources and accelerated transepithelial ('epi-on') methods.
  • Exploration of CXL in combination with refractive surgery (photorefractive keratectomy - PRK) and its application in treating infectious keratitis (PACK-CXL).

Key Points:

  • Advanced CXL techniques enable safer and more effective treatment of thin and ultra-thin corneas.
  • Accelerated 'epi-on' CXL procedures are emerging as alternatives to the traditional Dresden protocol.
  • CXL combined with PRK can achieve significant corneal flattening and regularization, expanding refractive surgery options.
  • Photoactivated chromophore for keratitis-corneal cross-linking (PACK-CXL) shows promise for treating infectious keratitis.

Conclusions:

  • CXL has diversified into multiple techniques with a broader range of indications.
  • Current CXL applications include managing corneal ectasias, refractive surgery, and treating infectious keratitis.