Related Experiment Video
Updated: Aug 1, 2025
09:31
Visualization of Gut Microbiota-host Interactions via Fluorescence In Situ Hybridization, Lectin Staining, and Imaging
Published on: July 9, 2021
8.4K
2022 Fleming Prize Lecture: diet-microbe-host interaction in early life
1Translational and Clinical Research Institute, Newcastle University, Newcastle, UK.
Journal of Medical Microbiology
|April 25, 2023
Summary
Human milk oligosaccharides (HMOs) promote beneficial infant gut bacteria, offering a potential strategy to prevent necrotizing enterocolitis in preterm infants. This research highlights the microbiome
Area of Science:
- Microbiology
- Human Microbiome Research
- Infant Health
Background:
- The human microbiome plays a critical role in health and disease.
- High-throughput sequencing has revolutionized microbial ecology studies.
- Infant gut microbiome development is crucial for early life health.
Approach:
- Review of recent research on the infant microbiome.
- Focus on the role of human milk oligosaccharides (HMOs).
- Examination of bacterial community modulation in early life.
Key Points:
- Human milk oligosaccharides (HMOs) promote Bifidobacterium spp. growth in the infant gut.
- This modulation is particularly relevant for preterm infants.
- Potential implications for preventing necrotizing enterocolitis in vulnerable infants.
Conclusions:
- Breast milk bioactive factors can shape the infant gut microbiome.
- Targeting the microbiome may improve health outcomes for preterm infants.
- Further mechanistic studies are needed to harness these factors for therapeutic benefit.
More Related Videos
Related Concept Videos
01:28Microbial Nutrition
136
Organisms exhibit remarkable metabolic diversity, categorized based on how they acquire energy and carbon. These strategies enable survival in various ecological niches and are essential for maintaining energy flow and nutrient cycling within ecosystems.Energy and Carbon SourcesOrganisms are classified as phototrophs or chemotrophs based on energy acquisition. Phototrophs use light as their energy source, while chemotrophs rely on oxidizing chemical compounds. Further differentiation arises...
136
01:23Dietary Connections
51.5K
In biological systems, most metabolic pathways are interconnected. The cellular respiration processes that convert glucose to ATP—such as glycolysis, pyruvate oxidation, and the citric acid cycle—tie into those that break down other organic compounds. As a result, various foods—from apples to cheese to guacamole—end up as ATP. In addition to carbohydrates, food also contains proteins and lipids—such as cholesterol and fats. All of these organic compounds are used...
51.5K
01:23Anatomy of the Intestines
72.7K
Although digestion of proteins, carbohydrates, and lipids may begin in the stomach, it is completed in the intestine. The absorption of nutrients, water, and electrolytes from food and drink also occurs in the intestine. The intestines can be divided into two structurally distinct organs—the small and large intestines.
Small Intestines
The small intestine is an ~7 meter-long tube with an inner diameter of just 2.5 cm. Since most nutrients are absorbed here, the inner lining of the...
Small Intestines
The small intestine is an ~7 meter-long tube with an inner diameter of just 2.5 cm. Since most nutrients are absorbed here, the inner lining of the...
72.7K
02:11The Roles of Bacteria and Fungi in Plant Nutrition
36.4K
Plants have the impressive ability to create their own food through photosynthesis. However, plants often require assistance from organisms in the soil to acquire the nutrients they need to function correctly. Both bacteria and fungi have evolved symbiotic relationships with plants that help the species to thrive in a wide variety of environments.
36.4K
01:28History of Microbiology
390
Microbiology, a scientific field dedicated to the study of microorganisms, has undergone profound development since its inception in the 17th century. Its history is marked by key discoveries and technological advancements that have shaped our understanding of life at the microscopic level and transformed medicine, agriculture, and industry.Early Foundations of MicrobiologyThe early foundations of microbiology were built on groundbreaking observations and the development of pioneering...
390
01:06Lipid Digestion
92.4K
Lipids are large molecules that are generally not water-soluble. Since most of the digestive enzymes in the human body are water-based, there are specific steps the body must take to break down lipids and make them available for use.
92.4K