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Updated: Aug 1, 2025

Directed Cellular Self-Assembly to Fabricate Cell-Derived Tissue Rings for Biomechanical Analysis and Tissue Engineering
Published on: November 25, 2011
Growth of a flexible fibre in a deformable ring
Arsenio Cutolo1, Massimiliano Fraldi1, Gaetano Napoli2
1Dipartimento di Strutture per l'Ingegneria e l'Architettura, Università di Napoli Federico II, Italy.
Abstract:
We study the equilibrium configurations related to the growth of an elastic fibre in a confining flexible ring. This system represents a paradigm for a variety of biological, medical, and engineering problems. We consider a simplified geometry in which initially the container is a circular ring of radius R. Quasi-static growth is then studied by solving the equilibrium equations as the fibre length l increases, starting from l = 2R. Considering both the fibre and the ring as inextensible and unshearable, we find that beyond a critical length, which depends on the relative bending stiffness, the fibre buckles. Furthermore, as the fibre grows further it folds, distorting the ring until it induces a break in mirror symmetry at l > 2πR. We get that the equilibrium shapes depend only on two dimensionless parameters: the length ratio μ = l/R and the bending stiffnesses ratio κ. These findings are also supported by finite element simulation. Finally we experimentally validate the theoretical results showing a very good quantitative prediction of the observed buckling and folding regimes at variable geometrical parameters.
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