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Updated: Aug 31, 2026

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Isolation of Primary Mouse Hepatocytes for Nascent Protein Synthesis Analysis by Non-radioactive L-azidohomoalanine Labeling Method
Published on: October 23, 2018
Daily changes of protein synthesis and secretion rates in rat liver slices
The International Journal of Biochemistry
|January 1, 1986
Abstract:
The rates of protein synthesis and secretion in rat liver slices showed temporal variability, as assessed by the use of [14C]leucine. The protein synthesis showed daily changes with two maxima at 13:00 and 01:00 hr and minimum at 17:00 hr. The secretion rate also varies within 24 hr showing biphasic pattern. The pattern of daily secretion rate for hydrophobic proteins differed from the pattern observed for acid proteins and glycoproteins.

