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Updated: Aug 15, 2026

High-frequency High-resolution Echocardiography: First Evidence on Non-invasive Repeated Measure of Myocardial Strain, Contractility, and Mitral Regurgitation in the Ischemia-reperfused Murine Heart
11:50

High-frequency High-resolution Echocardiography: First Evidence on Non-invasive Repeated Measure of Myocardial Strain, Contractility, and Mitral Regurgitation in the Ischemia-reperfused Murine Heart

Published on: July 10, 2010

[Real-time bidimensional-color Doppler evaluation of patent ductus arteriosus]

A Vitarelli, A Scapato, G Landolina

    Giornale Italiano Di Cardiologia
    |January 1, 1986
    PubMed

    Insights

    Real-time Doppler echocardiography effectively visualizes left-to-right shunts in patients with patent ductus arteriosus (PDA). This noninvasive method reliably assesses pulmonary artery pressure and shunt severity.

    Area of Science:

    • Cardiovascular imaging
    • Pediatric cardiology
    • Echocardiography

    Context:

    • Patent ductus arteriosus (PDA) is a common congenital heart defect.
    • Accurate assessment of shunt severity is crucial for management.
    • Noninvasive methods are preferred for pediatric patients.

    Purpose:

    • To evaluate the utility of real-time two-dimensional Doppler echocardiography for assessing left-to-right shunts at the ductal level.
    • To correlate echocardiographic findings with cardiac catheterization data.
    • To assess the noninvasive estimation of pulmonary artery pressure.

    Summary:

    • Eleven patients with PDA (1 day to 16 years) and 18 controls underwent Doppler echocardiography.
    • Echocardiography clearly visualized pulmonary flow patterns and ductal jet streams.
    • Colour-coded shunt area correlated with catheterization-derived shunt size.
    • Pharmacologic closure with indomethacin was observed in two infants.
    • Combined Doppler techniques provided reliable noninvasive pulmonary artery pressure assessment.

    Impact:

    • Doppler echocardiography offers a reliable, noninvasive tool for evaluating PDA severity.
    • This technique aids in clinical decision-making and treatment monitoring.
    • It reduces the need for invasive procedures like cardiac catheterization in pediatric patients.

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