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Inulin diet uncovers complex diet-microbiota-immune cell interactions remodeling the gut epithelium.

Renan Oliveira Corrêa1,2, Pollyana Ribeiro Castro3, José Luís Fachi3,4

  • 1Laboratory of Immunoinflammation, Department of Genetics, Evolution, Microbiology, and Immunology, Institute of Biology, University of Campinas, Campinas, SP, 13083-862, Brazil. renanocorrea@gmail.com.

Microbiome
|April 26, 2023
PubMed
Summary

Inulin promotes intestinal stem cell proliferation and colon remodeling, an effect dependent on gut microbiota, gamma delta T cells, and IL-22. This highlights complex diet-microbiota-immune interactions in the gut.

Keywords:
BacteroidalesEpithelial remodelingGut homeostasisHigh-fiber dietIL-22Intestinal stem cellsγδ T cells

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