[Ichthyosis uteri. Case report on a rare clinical entity].

Area of Science:

• Gynecologic Oncology
• Pathology
• Reproductive Medicine

Background:

• Ichthyosis uteri is a rare endometrial condition.
• Squamous cell metaplasia can precede malignant changes.
• Endometritis may be a contributing factor.

Observation:

• A case of squamous cell carcinoma of the corpus uteri was observed.
• The carcinoma developed at the base of ichthyosis uteri.
• The ichthyosis uteri progressed over three years from squamous cell metaplasia.

Findings:

• Ichthyosis uteri can undergo malignant transformation into squamous cell carcinoma.
• This progression can occur relatively quickly, within three years.
• Nonspecific endometritis was present during the development of ichthyosis uteri.

Implications:

• Hysterectomy is recommended upon diagnosis of ichthyosis uteri.
• Curettage is insufficient for eliminating these precancerous changes.
• Prompt surgical intervention is crucial to mitigate the risk of uterine cancer.