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Related Experiment Video

Updated: Aug 1, 2025

In Vivo Tracking of Edema Development and Microvascular Pathology in a Model of Experimental Cerebral Malaria Using Magnetic Resonance Imaging
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Retinal imaging technologies in cerebral malaria: a systematic review.

Kyle J Wilson1,2, Amit Dhalla3, Yanda Meng4

  • 1Department of Eye & Vision Sciences, University of Liverpool, Liverpool, UK. kyle.wilson@liverpool.ac.uk.

Malaria Journal
|April 26, 2023
PubMed
Summary

Retinal imaging aids in diagnosing and understanding cerebral malaria (CM). Advances in AI-assisted analysis of fundus photography and OCT offer real-time diagnostic potential, especially in resource-limited settings.

Keywords:
Cerebral malariaFluorescein angiographyFundus photographyMalarial retinopathyOptical coherence tomography

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Last Updated: Aug 1, 2025

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Area of Science:

  • Ophthalmology
  • Infectious Diseases
  • Medical Imaging

Background:

  • Cerebral malaria (CM) poses a significant global health burden, particularly in sub-Saharan Africa.
  • Malarial retinopathy (MR) is a key indicator in CM, offering diagnostic and prognostic value.
  • Retinal imaging advancements enhance the characterization of MR and insights into CM pathophysiology.

Conclusions:

  • Further research into retinal imaging technologies for CM is warranted.
  • Interdisciplinary collaboration is crucial for elucidating the complex pathophysiology of CM.
  • Retinal imaging, particularly with AI integration, shows significant potential for improving CM diagnosis and management.