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The national COPD screening programme in China: rationale and design.

Jieping Lei1,2,3,4, Ke Huang2,3,4,5, Jun Pan6

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China launched a nationwide COPD screening program to identify and manage high-risk individuals. This large-scale study will assess the program's impact on smoking cessation, morbidity, and mortality for chronic respiratory disease.

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Area of Science:

  • Pulmonary Medicine
  • Public Health
  • Epidemiology

Background:

  • Chronic Obstructive Pulmonary Disease (COPD) is a major public health concern in China, with a significant undetected high-risk population.
  • Early detection and intervention are crucial for managing COPD progression and improving patient outcomes.

Purpose of the Study:

  • To evaluate the net benefit of a nationwide COPD mass screening program in China.
  • To assess the program's impact on smoking cessation rates, morbidity, mortality, and health status in high-risk individuals.
  • To determine the diagnostic accuracy, cost-effectiveness, and superiority of the screening program.

Main Methods:

  • A multistage sequential screening program utilizing a validated COPD Screening Questionnaire and spirometry.
  • Recruitment of 800,000 participants aged 35-75 years across 31 provinces in China.
  • Integrated management and follow-up for at least one year for identified high-risk individuals and early COPD patients.

Main Results:

  • This is the first large-scale prospective study to evaluate the benefits of mass COPD screening in China.
  • The study will provide data on the effectiveness of the screening program in improving health outcomes.
  • The diagnostic accuracy and cost-effectiveness of the screening approach will be assessed.

Conclusions:

  • The nationwide COPD screening program represents a significant advancement in managing chronic respiratory diseases in China.
  • Findings will inform public health strategies for COPD prevention and control.
  • The study aims to establish the value of systematic screening in reducing the burden of COPD.