Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Experiment Videos

Gas vitrectomy in a primate model.

H Lincoff, I Kreissig, F Jakobiec

    Graefe'S Archive for Clinical and Experimental Ophthalmology = Albrecht Von Graefes Archiv Fur Klinische Und Experimentelle Ophthalmologie
    |January 1, 1986
    PubMed
    Summary
    This summary is machine-generated.

    Related Concept Videos

    You might also read

    Related Articles

    Articles linked to this work by shared authors, journal, and citation graph.

    Sort by
    Same author

    Intravitreal triamcinolone acetonide for treatment of central retinal vein occlusion.

    European journal of ophthalmology·2005
    Same author

    Cataract surgery combined with intravitreal injection of triamcinolone acetonide.

    European journal of ophthalmology·2005
    Same author

    [Intravitreal triamcinolone acetonide Complication of infectious and sterile endophthalmitis].

    Der Ophthalmologe : Zeitschrift der Deutschen Ophthalmologischen Gesellschaft·2005
    Same author

    Finding the retinal break in rhegmatogenous retinal detachment.

    Indian journal of ophthalmology·2005
    Same author

    Diffuse diabetic macular oedema treated by intravitreal triamcinolone acetonide: a comparative, non-randomised study.

    The British journal of ophthalmology·2005
    Same author

    Repeated intravitreal injection of triamcinolone acetonide for diffuse diabetic macular oedema.

    The British journal of ophthalmology·2004
    Same journal

    Association between angiogenic features and responsiveness to faricimab in treatment-naïve neovascular age-related macular degeneration with OCT angiography.

    Graefe's archive for clinical and experimental ophthalmology = Albrecht von Graefes Archiv fur klinische und experimentelle Ophthalmologie·2026
    Same journal

    Switching to aflibercept 8 mg in neovascular age-related macular degeneration: real-world outcomes according to switch indication.

    Graefe's archive for clinical and experimental ophthalmology = Albrecht von Graefes Archiv fur klinische und experimentelle Ophthalmologie·2026
    Same journal

    Correction of aphakia using biometry-based contact lens calculation in pediatric cataract extraction: introducing the aphakic contact lens formula.

    Graefe's archive for clinical and experimental ophthalmology = Albrecht von Graefes Archiv fur klinische und experimentelle Ophthalmologie·2026
    Same journal

    Management of full-thickness macular holes in patients with retinitis pigmentosa - a case series of 5 patients operated with pars plana vitrectomy.

    Graefe's archive for clinical and experimental ophthalmology = Albrecht von Graefes Archiv fur klinische und experimentelle Ophthalmologie·2026
    Same journal

    Association between probiotic prescriptions and the incidence of primary open-angle glaucoma in patients with documented dry eye.

    Graefe's archive for clinical and experimental ophthalmology = Albrecht von Graefes Archiv fur klinische und experimentelle Ophthalmologie·2026
    Same journal

    Clinical outcomes of 577-nm subthreshold micropulse laser therapy in chronic central serous chorioretinopathy: influence of retinal pigment epithelium alterations and baseline OCT characteristics.

    Graefe's archive for clinical and experimental ophthalmology = Albrecht von Graefes Archiv fur klinische und experimentelle Ophthalmologie·2026
    See all related articles

    Expanding perfluorocarbon gas bubbles compressed vitreous collagen against the retina in monkeys. This study clarifies vitreous behavior during gas tamponade, important for retinal detachment surgery.

    Area of Science:

    • Ophthalmology
    • Retinal Surgery
    • Vitreous Humor Research

    Background:

    • Perfluorocarbon gases are used in retinal detachment repair.
    • Understanding vitreous behavior during gas tamponade is crucial for surgical success.
    • Previous studies lacked detailed ultrastructural analysis of vitreous-retinal interactions.

    Purpose of the Study:

    • To investigate the ultrastructural changes in the vitreous humor during expansion of perfluorocarbon gas bubbles.
    • To determine the precise interaction between the expanding gas bubble and the retinal surface.
    • To clarify the mechanism of vitreous displacement and its effect on the retina.

    Main Methods:

    • Cynomolgus monkey model utilized for the study.
    • Expanding bubbles of perfluorocarbon gas were introduced to displace vitreous.

    Related Experiment Videos

  • Clinical observations and gross dissections were performed.
  • Electron microscopy of frozen sections provided ultrastructural analysis.

    • Main Results:

    • Clinical and gross examination suggested potential cortical vitreous stripping.
    • Electron microscopy revealed compression of the vitreous collagen structure against the retina.
    • No evidence of retinal stripping was confirmed at the ultrastructural level.

    Conclusions:

    • Perfluorocarbon gas expansion leads to vitreous collagen compression, not retinal stripping.
    • This finding refines the understanding of vitreous mechanics in gas tamponade procedures.
    • The study provides critical ultrastructural evidence for vitreous behavior during retinal surgery.