Recent Development of Functional Chitosan-Based Hydrogels for Pharmaceutical and Biomedical Applications

Area of Science:

• Biomaterials Science
• Polymer Chemistry
• Biomedical Engineering

Background:

• Chitosan, a naturally derived polysaccharide, is extensively researched for hydrogel applications.
• Chitosan-based hydrogels exhibit desirable properties including biocompatibility, biodegradability, and non-immunogenicity.
• These hydrogels possess multifunctional capabilities for drug encapsulation, carriage, and controlled release.

Purpose of the Study:

• To summarize advanced functions of chitosan-based hydrogels.
• To review fabrication methods and resultant properties from the past decade.
• To prospect future directions for pharmaceutical and biomedical applications.

Main Methods:

• Literature review focusing on publications from the recent decade.
• Analysis of fabrication techniques for chitosan-based hydrogels.
• Synthesis of information on hydrogel properties and applications.

Main Results:

• Chitosan hydrogels demonstrate significant potential in drug delivery systems.
• Recent progress shows applications in tissue engineering, disease treatments, and biosensors.
• Fabrication methods and resulting properties are detailed, showcasing versatility.

Conclusions:

• Chitosan-based hydrogels are highly promising for advanced pharmaceutical and biomedical applications.
• Continued research into fabrication and properties will drive innovation.
• Future development should focus on overcoming current challenges for broader clinical translation.