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Related Concept Videos

Pericarditis II: Clinical Features and Diagnostic Tests01:19

Pericarditis II: Clinical Features and Diagnostic Tests

13
Pericarditis is distinguished by inflammation of the pericardium, the fibrous sac that encases the heart. It can be acute, lasting less than six weeks, or chronic, persisting for over three months. Understanding its clinical manifestations and diagnostic findings is crucial for timely and effective management.Clinical ManifestationsWhile pericarditis can be asymptomatic, it usually presents with characteristic symptoms such as:Chest Pain: The most characteristic symptom of pericarditis is chest...
13
Pericarditis I: Introduction01:22

Pericarditis I: Introduction

14
Pericarditis is defined as the inflammation of the pericardium, the thin, sac-like membrane surrounding the heart. This condition can cause significant chest pain and other symptoms, often necessitating medical intervention. The pericardium has two layers: the inner visceral layer and the outer parietal layer, separated by a small amount of fluid that reduces friction during heartbeats.Types of PericarditisPericarditis can be classified into several types based on the duration and nature of the...
14
Pleural Disorders: Types and Brief Description01:30

Pleural Disorders: Types and Brief Description

261
The pleura is a vital part of the respiratory system. It's a double-layered membrane surrounding the lungs and lining the chest cavity. The two layers of the pleura are:
261
Pericarditis III: Medical Management01:17

Pericarditis III: Medical Management

18
The primary objectives of managing pericarditis are to determine the underlying cause, provide effective therapy for treatment and symptom relief, and promptly detect signs and symptoms of cardiac tamponade. The following outlines the essential aspects of medical management for pericarditis:ObjectivesDetermine the Cause: Identifying the underlying cause of pericarditis is crucial for targeted treatment. Causes include viral infections, autoimmune diseases, post-cardiac injury syndrome, and...
18
Myocarditis II: Clinical Features and Diagnostic Tests01:27

Myocarditis II: Clinical Features and Diagnostic Tests

14
Myocarditis is an inflammation of the heart muscle. The symptoms vary widely, encompassing asymptomatic presentations to severe, acute manifestations.Clinical PresentationAsymptomatic cases: In some instances, myocarditis may be asymptomatic, with the infection resolving without intervention. These cases often go undetected unless discovered incidentally through diagnostic imaging or tests conducted for other reasons.General Early Symptoms: Early symptoms of myocarditis are non-specific and can...
14
Pericarditis IV: Nursing Management01:25

Pericarditis IV: Nursing Management

24
Pericarditis, an inflammation of the pericardium, necessitates diligent nursing management to ensure effective patient care and recovery. The initial step in managing pericarditis is a comprehensive patient medical assessment.The patient reports chest pain aggravated by breathing, coughing, and swallowing, which worsens when lying supine. The pain often improves when sitting up and leaning forward. Additional symptoms may include fever, malaise, and, in severe cases, signs of heart failure.
24

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Related Experiment Video

Updated: Aug 1, 2025

Orthotopic Implantation and Peripheral Immune Cell Monitoring in the II-45 Syngeneic Rat Mesothelioma Model
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Pericardial Mesotheliomas.

Andrea Valeria Arrossi1

  • 1Cleveland Clinic, Cleveland, OH.

Advances in Anatomic Pathology
|April 27, 2023
PubMed
Summary

Primary pericardial mesothelioma (PM) is a rare but common primary pericardial cancer. Diagnosis requires tissue sampling and imaging, with poor prognosis and limited research due to its rarity.

Area of Science:

  • Oncology
  • Pathology

Background:

  • Primary pericardial mesothelioma (PM) is a rare tumor (<0.05% incidence), the most common primary pericardial malignancy.
  • Distinguishing PM from secondary involvement is crucial, as asbestos association is less documented than other mesotheliomas.
  • Late presentation with nonspecific symptoms related to cardiac constriction or tamponade is common.

Purpose of the Study:

  • To review the epidemiology, diagnosis, histology, and prognosis of primary pericardial mesothelioma.
  • To highlight diagnostic challenges and the importance of tissue sampling and immunohistochemistry.
  • To underscore the poor prognosis and limitations in research due to PM's rarity.

Main Methods:

  • Review of existing literature on primary pericardial mesothelioma.

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  • Analysis of diagnostic modalities including echocardiography, CT, and MRI.
  • Histopathological classification and immunohistochemical markers.

    • Main Results:

    • PM presents with thickened, enhancing pericardium, often encasing the heart, leading to constrictive physiology.
    • Histologically classified as epithelioid, sarcomatoid, or biphasic (most common).
    • Poor prognosis with approximately 22% 1-year survival.

    Conclusions:

    • Primary pericardial mesothelioma is a rare, challenging diagnosis with poor outcomes.
    • Multimodality imaging and tissue analysis are essential for accurate diagnosis.
    • Further research is needed to improve understanding and treatment, despite rarity limitations.