Characteristics of HRT users in Japan: Evidence from the Japan Nurses' Health Study
Toshiyuki Yasui1, Yuki Ideno2, Kazue Nagai2
1Department of Reproductive and Menopausal Medicine, Tokushima University Graduate School, Tokushima, Japan.
Objectives:
Little is known about what type of women use hormone replacement therapy (HRT) in Japan. Based on the Japan Nurses' Health Study (JNHS), a large population cohort study, we determined the characteristics of HRT users by comparing the characteristics of new HRT users and the characteristics of women who did not use HRT during a 10-year follow-up period.
Study Design:
Of the 15,019 JNHS participants, 4886 women reported an experience of menopausal transition during the 10-year follow-up period.
Main Outcome Measurement:
Characteristics of new HRT users.
Results:
The proportion of HRT users during the 10-year period was 8.5 %. Advanced age at menopause was significantly associated with a low rate of use of HRT. Past use of oral contraceptives, dysmenorrhea with disturbance in daily life and vasomotor symptoms were significantly associated with a high rate of use of HRT. The occupations of public health nurse and midwife and a history of bilateral oophorectomy were also significantly associated with a high rate of use of HRT.
Conclusions:
We determined the characteristics of new HRT users among middle-aged women during a 10-year follow-up period. Women who had sufficient knowledge about endocrinological hormones and women who had less reluctance to visit doctors for gynecological problems were likely to use HRT.
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