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Related Experiment Video

Updated: Aug 1, 2025

Treatment of Ligament Constructs with Exercise-conditioned Serum: A Translational Tissue Engineering Model
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Publication trends in ligament augmentation techniques: current concepts.

Sergei O Alexeev1, Sara E Buckley2, Michael A Hewitt2

  • 1University of South Carolina School of Medicine, Columbia, SC 29209, USA.

Journal of ISAKOS : Joint Disorders & Orthopaedic Sports Medicine
|April 27, 2023
PubMed
Summary
This summary is machine-generated.

Ligament augmentation techniques (LATs) are increasingly used in surgery. Recent literature shows a significant rise in LAT publications, particularly for knee and ankle ligaments, with novel fixation devices gaining popularity.

Keywords:
Internal braceLigamentLigament augmentationTightrope

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Area of Science:

  • Orthopedic Surgery
  • Biomedical Engineering
  • Sports Medicine

Background:

  • Ligament augmentation techniques (LATs) involve reinforcing anatomical ligament repair or reconstruction with synthetic materials.
  • LATs have seen a notable increase in clinical application and academic literature over the past decade.
  • Understanding trends in LAT publications aids in identifying evidence-based practices and research gaps.

Approach:

  • A systematic review of English-language literature published before May 24th, 2022, was conducted.
  • PubMed, Embase, and Cochrane CENTRAL databases were searched for studies on LATs involving human, cadaveric, or biomechanical models.
  • Data from 283 selected publications were analyzed using descriptive statistics.

Key Points:

  • Publications on LATs have expanded significantly, with 60.4% published since 2017, showing an 11% average annual increase since 2015.
  • Knee ligaments, especially the anterior cruciate ligament (31.8%), are the primary focus, but LATs are increasingly applied to ankle syndesmosis and coracoclavicular ligaments.
  • Novel fixation devices, such as suture buttons and anchors, are frequently reported in recent literature.

Conclusions:

  • This review defines LATs and quantifies their growing presence in scientific literature.
  • The findings offer physicians insights into the historical development and diverse applications of LATs.
  • The data highlights the expanding scope and evolving techniques within ligament augmentation research.