Related Experiment Video
Updated: Aug 1, 2025

Left Atrial Stenosis Induced Pulmonary Venous Arterialization and Group 2 Pulmonary Hypertension in Rat
Published on: November 18, 2018
[Pulmonary hypertension associated with lung disease]
Manuel J Richter1,2, Khodr Tello3,4
1Medizinische Klinik II, Universitätsklinikum Gießen und Marburg, Klinikstraße 32, 35392, Gießen, Deutschland. manuel.richter@innere.med.uni-giessen.de.
Pulmonary hypertension (PH) in group 3, linked to lung disease, presents diagnostic challenges. Severe PH (PVR > 5 WU) requires specific management, while milder cases focus on the underlying lung condition.
Area of Science:
- Cardiology
- Pulmonology
- Vascular Medicine
Related Concept Videos
Pulmonary Hypertension: Classification and Pathogenesis
There are various classifications for PH, each relating to different underlying causes and also...
Treatment for Pulmonary Arterial Hypertension: Oxygen Therapy for Respiratory Failure
Oxygen therapy is vital in increasing and maintaining blood oxygen levels in PAH patients. As a result, it aids in reducing fatigue,...
Chronic Obstructive Pulmonary Disease-III: Symptoms and Complications.
Symptoms of COPD can be classified as primary or systemic. Primary symptoms relate to reduced airflow, while systemic or extrapulmonary symptoms relate to COPD's broader impact on the body.
Primary Symptoms of COPD:
Pulmonary Embolism I: Introduction
Other Pulmonary Disorders
Treatment for Pulmonary Arterial Hypertension: Phosphodiesterase Inhibitors
Among the PDE5 inhibitors, sildenafil (Revatio) stands out as a competitive and selective inhibitor. It operates by elevating cellular levels of cGMP and augmenting signaling through the cGMP-PKG pathway, promoting vasodilation. Upon oral...

