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Are we getting closer to offering deep brain stimulation for treatment-resistant depression in clinical practice?

Liming Qiu1, Casey H Halpern1,2, Daniel A N Barbosa3

  • 1Department of Neurosurgery, Perelman School of Medicine, University of Pennsylvania, Philadelphia, PA, USA.

Molecular Psychiatry
|April 27, 2023
PubMed
Abstract

No abstract available in PubMed .

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Electroconvulsive therapy (ECT), or shock therapy, remains a critical biomedical intervention for severe, treatment-resistant depression. While its origins can be traced back to Hippocrates' observations that malaria-induced convulsions alleviated mental illness, modern ECT has evolved significantly from its earlier, more primitive applications. First introduced in 1938 by Ugo Cerletti and his colleagues, ECT involves inducing controlled seizures using electrical currents. In its early...
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