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Characterizing DNA Repair Processes at Transient and Long-lasting Double-strand DNA Breaks by Immunofluorescence Microscopy
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Characterizing DNA Repair Processes at Transient and Long-lasting Double-strand DNA Breaks by Immunofluorescence Microscopy

Published on: June 8, 2018

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Special Issue "DNA Replication/Repair, and the DNA Damage Response in Human Disease"

Dong Zhang1,2, Kristin A Eckert3, Marietta Y W T Lee4

  • 1Department of Biomedical Sciences, College of Osteopathic Medicine, New York Institute of Technology, Old Westbury, NY 11568, USA.

Genes
|April 28, 2023
PubMed

Insights

Mutations in DNA replication, repair, and damage response genes cause diseases like cancer and aging. Understanding these genetic pathways is crucial for disease prevention and treatment.

Area of Science:

  • Genetics and Molecular Biology
  • Cellular Biology
  • Disease Mechanisms

Background:

  • Genetic mutations in DNA replication, repair, and DNA damage response (DDR) pathways are linked to various human diseases.
  • These pathways are fundamental for maintaining genomic stability and preventing disease development.

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