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OBHS Drives Abnormal Glycometabolis Reprogramming via GLUT1 in Breast Cancer

Kexin Wang1, Qiuzi Li1, Yufeng Fan1

  • 1Hubei Key Laboratory of Cell Homeostasis, College of Life Sciences, Wuhan University, Bayi Road, Wuhan 430072, China.

International Journal of Molecular Sciences
|April 28, 2023
PubMed
Summary

Oxabicycloheptene sulfonate (OBHS) targets breast cancer's abnormal sugar metabolism by inhibiting glucose transporter 1 (GLUT1). This reduces tumor growth and ATP production, offering a potential new therapy for breast cancer patients.

Keywords:
GLUT1OBHSbreast cancercombination therapyglycometabolism

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