Related Experiment Video
Updated: Jul 29, 2026
07:56
Author Spotlight: Advanced Enteroid Model for Studying Host-Pathogen Interactions
Published on: April 5, 2024
1.9K
Editorial of Special Issue "Human Pathogenic Fungi: Host-Pathogen Interactions and Virulence"
Samir Jawhara1,2,3
1UMR 8576-UGSF-Unité de Glycobiologie Structurale et Fonctionnelle, Centre National de la Recherche Scientifique, F-59000 Lille, France.
Microorganisms
|April 28, 2023
Abstract:
Most individuals harbour several species of yeast of the genus Candida, which are considered true symbionts of the human gut microbiota [...].
Insights
Most people carry Candida yeast species in their gut microbiota. These fungi are usually harmless symbionts, playing a role in the complex ecosystem of the human digestive tract.
Area of Science:
- Microbiology
- Mycology
- Human Microbiome Research
Background:
- Candida yeasts are common inhabitants of the human gut microbiota.
- These fungi are generally considered commensal or symbiotic organisms.
- The presence of multiple Candida species is typical in healthy individuals.
Discussion:
- Investigating the symbiotic relationship between Candida and the human gut microbiome.
- Understanding the ecological role of Candida species within the digestive tract.
- Exploring the factors influencing Candida colonization and persistence.
Key Insights:
- Candida yeasts are integral components of the human gut microbiome.
- The symbiotic nature of Candida suggests a co-evolved relationship with the host.
- Further research is needed to fully elucidate the functional implications of Candida symbiosis.
Outlook:
- Future studies should focus on the functional impact of Candida symbiosis on host health.
- Investigating potential shifts in Candida populations and their association with disease states.
- Exploring therapeutic strategies that modulate Candida populations within the gut microbiome.
Related Concept Videos
02:11The Roles of Bacteria and Fungi in Plant Nutrition
Plants have the impressive ability to create their own food through photosynthesis. However, plants often require assistance from organisms in the soil to acquire the nutrients they need to function correctly. Both bacteria and fungi have evolved symbiotic relationships with plants that help the species to thrive in a wide variety of environments.
01:28Fungal Phylum Microsporidia
Microsporidia are a group of obligate intracellular fungi that were initially classified as protists but were later reclassified based on phylogenetic, molecular, and structural evidence linking them to the Chytridiomycota. These unicellular, non-motile organisms are highly specialized parasites that infect a wide range of animal hosts, including humans. They have evolved extensive genomic and metabolic reductions, making them highly dependent on their hosts for survival.Morphology and Genomic...
01:22Microbial Interactions: Parasitism
Parasitism is a form of microbial interaction in which parasitic microbes exploit a host organism for nutrients and shelter, often at the host's expense. Unlike mutualistic relationships, where both organisms benefit, parasitism benefits only the parasite and harms the host.Classification of ParasitesMicrobial parasites are broadly classified based on their location relative to the host.Ectoparasites remain on the host’s surface, such as the skin or outer tissues, drawing nutrients...
01:09Microbe-Plant Interactions
Microbe-plant interactions represent a dynamic spectrum of associations shaped by intricate chemical signaling. These interactions can be neutral, beneficial, or detrimental, and profoundly influence plant physiology, growth, and ecosystem function. The plant microbiome, comprising bacteria, fungi, archaea, protists, and viruses, plays a pivotal role in mediating these effects through surface colonization, internal colonization, or systemic symbiosis.Mutualistic associations, particularly with...
01:25Colonisation of Pathogens
Pathogen colonization of host tissues is a critical step in the development of infectious diseases. Various pathogenic microorganisms, including bacteria, fungi, viruses, and protozoa, have evolved complex strategies to attach to, invade, and persist within host environments. These mechanisms enable pathogens to establish infections, evade immune responses, and resist antimicrobial treatments.Attachment to Host CellsIn bacteria, colonization typically begins with adherence to host epithelial...
01:20Determinants of Bacterial Pathogenicity and Virulence
Pathogenic bacteria employ a variety of strategies to establish infections, including the secretion of extracellular enzymes that act as potent virulence factors. These enzymes facilitate bacterial colonization of host tissues and help evade immune surveillance. By targeting structural components of host tissues and interfering with immune mechanisms, these enzymes play a pivotal role in disease progression.Extracellular Enzymes Facilitating Tissue Invasion: Several bacterial pathogens secrete...