Related Experiment Video

Updated: Aug 1, 2025

Live Imaging and Quantification of Viral Infection in K18 hACE2 Transgenic Mice Using Reporter-Expressing Recombinant SARS-CoV-2
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Live Imaging and Quantification of Viral Infection in K18 hACE2 Transgenic Mice Using Reporter-Expressing Recombinant SARS-CoV-2

Published on: November 5, 2021

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Special Issue: Advances in SARS-CoV-2 Infection

Carlo Contini1, John Charles Rotondo2,3, Benedetta Perna4

  • 1Infectious and Dermatology Diseases, St. Anna University-Hospital of Ferrara, University of Ferrara, 44124 Ferrara, Italy.

Microorganisms
|April 28, 2023
PubMed

Insights

Severe Acute Respiratory Syndrome Coronavirus 2 (SARS-CoV-2) causes COVID-19, a dangerous respiratory illness. This virus rapidly spread globally starting in late 2019.

Area of Science:

  • Virology
  • Epidemiology
  • Public Health

Background:

  • The emergence of Coronavirus Disease 2019 (COVID-19) in late 2019 marked a significant global health crisis.
  • COVID-19 is caused by the novel Severe Acute Respiratory Syndrome Coronavirus 2 (SARS-CoV-2).
  • The virus rapidly disseminated worldwide, leading to a global pandemic.

Discussion:

  • Understanding the origins and transmission dynamics of SARS-CoV-2 is crucial for pandemic response.
  • The rapid spread highlights the interconnectedness of global health systems.
  • Ongoing research is vital to comprehend the full impact of SARS-CoV-2.

Key Insights:

  • SARS-CoV-2 is the causative agent of COVID-19.
  • The virus's origin was traced to late 2019 in China.
  • Global spread resulted in a worldwide pandemic.

Outlook:

  • Continued surveillance and research into SARS-CoV-2 are essential.
  • Developing effective countermeasures remains a priority.
  • International collaboration is key to managing future viral threats.

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