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Updated: Aug 1, 2025

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Live Imaging and Quantification of Viral Infection in K18 hACE2 Transgenic Mice Using Reporter-Expressing Recombinant SARS-CoV-2
Published on: November 5, 2021
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Special Issue: Advances in SARS-CoV-2 Infection
Carlo Contini1, John Charles Rotondo2,3, Benedetta Perna4
1Infectious and Dermatology Diseases, St. Anna University-Hospital of Ferrara, University of Ferrara, 44124 Ferrara, Italy.
Microorganisms
|April 28, 2023
Summary
Severe Acute Respiratory Syndrome Coronavirus 2 (SARS-CoV-2) causes COVID-19, a dangerous respiratory illness. This virus rapidly spread globally starting in late 2019.
Area of Science:
- Virology
- Epidemiology
- Public Health
Background:
- The emergence of Coronavirus Disease 2019 (COVID-19) in late 2019 marked a significant global health crisis.
- COVID-19 is caused by the novel Severe Acute Respiratory Syndrome Coronavirus 2 (SARS-CoV-2).
- The virus rapidly disseminated worldwide, leading to a global pandemic.
Discussion:
- Understanding the origins and transmission dynamics of SARS-CoV-2 is crucial for pandemic response.
- The rapid spread highlights the interconnectedness of global health systems.
- Ongoing research is vital to comprehend the full impact of SARS-CoV-2.
Key Insights:
- SARS-CoV-2 is the causative agent of COVID-19.
- The virus's origin was traced to late 2019 in China.
- Global spread resulted in a worldwide pandemic.
Outlook:
- Continued surveillance and research into SARS-CoV-2 are essential.
- Developing effective countermeasures remains a priority.
- International collaboration is key to managing future viral threats.
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