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How to Promote Skin Repair? In-Depth Look at Pharmaceutical and Cosmetic Strategies.

Ana Torres1,2, Liliana Rego1,2, Márcia S Martins3,4

  • 1UCIBIO-Applied Molecular Biosciences Unit, MedTech, Laboratory of Pharmaceutical Technology, Department of Drug Sciences, Faculty of Pharmacy, University of Porto, 4050-313 Porto, Portugal.

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Summary

This study analyzed skin repair ingredients in Portuguese pharmacies, identifying top choices in cosmetics, medicines, and medical devices. Metal salts, oxides, and vitamin E were most frequent in cosmetics, while silicones dominated medical devices.

Keywords:
epidermal barriermetal oxides and saltsscientific evidenceskin repairtrendswound healing

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Area of Science:

  • Dermatology
  • Cosmetology
  • Pharmacology

Background:

  • Skin repair is crucial for epidermal barrier function and wound healing, involving complex biological processes.
  • Numerous strategies and ingredients are utilized in cosmetic, medicinal, and medical device formulations for skin repair.
  • Understanding ingredient prevalence is key for evidence-based product development and clinical recommendations.

Purpose of the Study:

  • To determine the usage frequency of skin repair ingredients in commercialized products in Portugal.
  • To identify the top skin repair ingredients across cosmetics, topical medicines, and medical devices.
  • To critically review the efficacy of prevalent ingredients and analyze the top three.

Main Methods:

  • A comprehensive analysis of product compositions was conducted.
  • 120 cosmetic products, 21 topical medicines, and 46 medical devices were analyzed.
  • Data was sourced from online pharmacy platforms and the INFARMED database.

Main Results:

  • Cosmetics: Metal salts/oxides (78.3%), Vitamin E derivatives (54.2%), Centella asiatica extract (35.8%).
  • Medicines: Metal salts/oxides (47.4%), Vitamin B5 derivatives (23.8%), Vitamin A derivatives (26.3%).
  • Medical Devices: Silicones (33%), Petrolatum derivatives (22%), Alginate (15%).

Conclusions:

  • Identified the most frequently used skin repair ingredients across different product categories.
  • Provided insights into ingredient trends in the Portuguese market.
  • Aimed to support healthcare professionals with an updated overview of skin repair ingredients and their mechanisms.