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Updated: Aug 1, 2025

Magnetic Resonance Imaging Assessment of Carcinogen-induced Murine Bladder Tumors
Published on: March 29, 2019
PET Imaging in Bladder Cancer: An Update and Future Direction
Jules Zhang-Yin1, Antoine Girard2, Etienne Marchal2
1Department of Nuclear Medicine, Clinique Sud Luxembourg, Vivalia, B-6700 Arlon, Belgium.
Positron emission tomography (PET) is vital for bladder cancer management, aiding in staging, follow-up, and treatment guidance. Future advancements in radiopharmaceuticals and AI promise enhanced diagnostic capabilities for bladder cancer patients.
Area of Science:
- Oncology
- Nuclear Medicine
- Radiology
Background:
- Molecular imaging with positron emission tomography (PET) plays a crucial role in managing bladder cancer.
- Current applications include staging, follow-up, and treatment guidance.
Purpose of the Study:
- To review the current role of PET imaging in bladder cancer care.
- To explore future advancements in radiopharmaceuticals and technology for bladder cancer management.
Main Methods:
- Review of [18F]2-[18F]fluoro-2-deoxy-D-glucose (FDG) PET/CT and PET/MRI in bladder cancer.
- Discussion of novel PET radiopharmaceuticals beyond FDG, including fibroblast activation protein inhibitors.
- Exploration of artificial intelligence applications in PET imaging for bladder cancer.
Main Results:
- [18F]FDG PET/CT is established for staging and follow-up of bladder cancer.
- PET/MRI offers complementary diagnostic information.
- Emerging radiotracers and AI show potential for improved accuracy and personalized treatment.
Conclusions:
- PET imaging is integral to modern bladder cancer management.
- Future innovations in radiopharmaceuticals and AI will further refine diagnostic and therapeutic strategies.
- Continued research is essential to fully leverage advanced PET techniques in bladder cancer care.
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