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Targeting the HIV-1 and HBV Capsids, an EnCore

William M McFadden1,2, Stefan G Sarafianos1,2

  • 1Center for ViroScience and Cure, Laboratory of Biochemical Pharmacology, Department of Pediatrics, Emory University School of Medicine, Atlanta, GA 30322, USA.

Viruses
|April 28, 2023
PubMed

Abstract:

Not many structures are common among all viruses: only nucleic acid and a protein coat [...].

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RNA viruses are categorized into positive-strand, negative-strand, or double-stranded groups based on their genomic structure and replication mechanisms. This classification dictates how they exploit host cellular machinery for protein synthesis and replication. Some RNA viruses also utilize reverse transcription as part of their life cycle, further diversifying their replication strategies.Positive-Strand RNA VirusesPositive-strand RNA viruses have genomes that function directly as messenger...
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