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Updated: Aug 1, 2025

Multiplex Therapeutic Drug Monitoring by Isotope-dilution HPLC-MS/MS of Antibiotics in Critical Illnesses
Published on: August 30, 2018
Global collaborations in antimicrobial stewardship: All hands on deck.
Diane Ashiru-Oredope1,2, Bradley J Langford3,4, Candice Bonaconsa5
1HCAI, Fungal, AMR, AMU & Sepsis Division, UK Health Security Agency, London, UK.
Global collaboration is crucial for antimicrobial stewardship (AMS) to combat antimicrobial resistance (AMR). This paper explains the need for international AMS efforts and offers guidance for initiating global health initiatives.
Area of Science:
- Global Health
- Infectious Disease Control
- Public Health Policy
Background:
- Antimicrobial resistance (AMR) poses a significant global health threat.
- The World Health Organization (WHO) identifies antimicrobial stewardship (AMS) as a key strategy against AMR.
- Effective AMR containment requires coordinated international action.
Purpose of the Study:
- To underscore the necessity of global collaborations for effective AMS.
- To present successful examples of international AMS initiatives.
- To provide practical considerations for establishing new global AMS programs.
Main Methods:
- Literature review of existing global AMS collaborations.
- Analysis of factors contributing to successful international health partnerships.
- Synthesis of expert recommendations for global health program development.
Main Results:
- Identified critical drivers for global AMS cooperation, including shared data and standardized guidelines.
- Highlighted successful models of international partnerships in combating AMR.
- Outlined key challenges and facilitators for initiating and sustaining global AMS efforts.
Conclusions:
- Global collaboration is indispensable for advancing antimicrobial stewardship and mitigating AMR.
- Strategic planning and resource sharing are vital for successful international AMS initiatives.
- The findings offer a roadmap for organizations seeking to engage in global health security efforts against AMR.
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