Related Experiment Video
Updated: Aug 1, 2025

Analyzing Beneficial Effects of Nutritional Supplements on Intestinal Epithelial Barrier Functions During Experimental Colitis
Published on: January 5, 2017
Unconventional but effective: breaking through IBS-D clinical practice guidelines - correspondence
Omer Ahmed Shaikh1, Gulrukh Shaikh2, Rameel Muhammad Aftab1
1Department of Medicine, Ziauddin University.
New guidelines offer a structured approach to managing Irritable Bowel Syndrome with diarrhea (IBS-D). This involves specific medication recommendations for a more personalized treatment plan for IBS-D patients.
Area of Science:
- Gastroenterology
- Clinical Medicine
Background:
- Irritable Bowel Syndrome with diarrhea (IBS-D) is a common, persistent gastrointestinal disorder.
- Traditional IBS-D management included dietary fiber, opioids, and antispasmodics.
Purpose of the Study:
- To present a modified approach to IBS-D management based on recent guidelines.
- To outline a tailored treatment strategy for IBS-D.
Main Methods:
- Review and incorporation of the American Gastroenterology Association's (AGA) recent treatment guideline for IBS-D.
- Development of a structured set of medication recommendations.
Main Results:
- The AGA guideline provides eight specific drug recommendations for IBS-D.
- A framework for selecting appropriate medications based on patient needs was devised.
Conclusions:
- The new guidelines facilitate a more tailored and focused management of IBS-D.
- Structured guidelines can improve the precision of IBS-D treatment strategies.
Related Concept Videos
Drugs for Treatment of Diarrhea-Predominant IBS
Two specific drugs used in the treatment are alosetron (Lotronex) and eluxadoline (Viberzi). Alosetron, a 5-HT3 antagonist, works by slowing the movement of stools in the gut, reducing bowel...
Irritable Bowel Syndrome III: Medical and Nursing Management
Irritable Bowel Syndrome II: Clinical Features and Diagnostic Evaluation
Irritable Bowel Syndrome (IBS) is classified into subtypes based on the predominant bowel habits as determined by the Bristol Stool Form Scale (BSFS). The subtypes are:
Inflammatory Bowel Disease III: Diagnostic Studies and Management I-Nutritional Therapy
Diagnostic studies
A colonoscopy is the definitive screening test, distinguishing ulcerative colitis from other colon diseases with similar symptoms. During a colonoscopy test, inflamed mucosa with exudate ulcerations can be observed, and biopsies are taken to determine the histologic characteristics of the...
Drugs for Treatment of Constipation-Predominant IBS
Irritable Bowel Syndrome I: Introduction
IBS is a chronic condition that can persist over a long period or recur frequently.
The pathogenesis of IBS involves a complex interplay of the following factors:
Altered...

