Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Experiment Videos

Increased muscle tone during etretinate therapy.

C N Ellis, M Gilbert, K A Cohen

    Journal of the American Academy of Dermatology
    |May 1, 1986
    PubMed
    Summary

    Severe psoriasis patients on etretinate may experience muscle stiffness, a potential side effect mimicking stiff-man syndrome. This symptom, relieved by nerve blocks, requires careful distinction from typical retinoid-related musculoskeletal issues.

    Related Concept Videos

    You might also read

    Related Articles

    Articles linked to this work by shared authors, journal, and citation graph.

    Sort by
    Same author

    Disease activity and treatment efficacy using patient-level Psoriasis Area and Severity Index scores from tildrakizumab phase 3 clinical trials.

    The Journal of dermatological treatment·2020
    Same author

    Excessive coupling of the salience network with intrinsic neurocognitive brain networks during rectal distension in adolescents with irritable bowel syndrome: a preliminary report.

    Neurogastroenterology and motility·2015
    Same author

    Comparison of three methods for measuring psoriasis severity in clinical studies (Part 2 of 2): use of quality of life to assess construct validity of the Lattice System Physician's Global Assessment, Psoriasis Area and Severity Index and Static Physician's Global Assessment.

    Journal of the European Academy of Dermatology and Venereology : JEADV·2015
    Same author

    Comparison of three methods for measuring psoriasis severity in clinical studies (Part 1 of 2): change during therapy in Psoriasis Area and Severity Index, Static Physician's Global Assessment and Lattice System Physician's Global Assessment.

    Journal of the European Academy of Dermatology and Venereology : JEADV·2015
    Same author

    7-5 by '05.

    Archives of dermatology·2014
    Same author

    Assessment of comparative skills between hand-assisted and straight laparoscopic colorectal training on an augmented reality simulator.

    Diseases of the colon and rectum·2010

    Area of Science:

    • Neurology
    • Dermatology
    • Pharmacology

    Background:

    • Psoriasis is a chronic inflammatory skin condition.
    • Retinoids, like etretinate, are used to treat severe psoriasis.
    • Musculoskeletal side effects are known with retinoid therapy.

    Observation:

    • A 40-year-old male psoriasis patient developed painless muscle stiffness during etretinate treatment.
    • The patient underwent four successive courses of etretinate therapy.
    • Peripheral nerve block provided relief from the increased muscle tone.

    Findings:

    • The patient's symptoms were consistent with stiff-man syndrome.
    • Increased muscle tone is identified as a potential adverse effect of etretinate.
    • This condition needs differentiation from common musculoskeletal symptoms associated with retinoids.

    Related Experiment Videos

    Implications:

    • Highlights a rare neurological side effect of etretinate therapy.
    • Emphasizes the importance of recognizing and distinguishing etretinate-induced muscle stiffness.
    • Informs clinical practice for managing psoriasis patients on retinoid treatments.