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Related Concept Videos

Skin Cancer01:30

Skin Cancer

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Skin cancer is a type of cancer that occurs when there is an abnormal growth of skin cells, usually triggered by damage to the DNA within the skin cells. It is primarily caused by exposure to ultraviolet (UV) radiation from the sun or artificial sources like tanning beds. Skin cancer is the most common type of cancer worldwide, and its incidence continues to rise.
Basal Cell Carcinoma (BCC): BCC is the most common type of skin cancer, accounting for about 80% of cases. It typically develops in...
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Skin Diseases and Disorders01:23

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Skin is the first line of defense and encounters a variety of microbes. Some pathogenic strains are often the cause of a broad range of infections of the skin and other body systems. These conditions can affect people of all ages and may have different causes, including genetic factors, infections, autoimmune reactions, environmental factors, and lifestyle choices.
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SBAR II: Application of SBAR01:14

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SBAR is an effective communication tool used by healthcare professionals to communicate patient information accurately. SBAR stands for Situation, Background, Assessment, and Recommendation. For a better understanding, an example is given below.
SBAR Report from a Nurse to a Health Care Provider
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Accessory Structures of the Skin: Sebaceous Glands01:21

Accessory Structures of the Skin: Sebaceous Glands

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A sebaceous gland is a type of oil gland found almost all over the skin ( except palms and soles) and helps lubricate and waterproof the skin and hair. Most sebaceous glands are associated with hair follicles. They generate and excrete sebum, a mixture of lipids, onto the skin surface, thereby naturally lubricating the dry and dead layer of keratinized cells of the stratum corneum, keeping it pliable.
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Cell Motility through Blebbing01:16

Cell Motility through Blebbing

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Blebs are a type of membrane protrusion formed by the internal hydrostatic pressure of the cytoplasm. Blebs are observed in several cell types, including fibroblasts, immune cells, and single-celled organisms like the amoeba. The primary function of blebs is cell locomotion and apoptosis, but they are also found during necrosis and cell division. The life cycle of a bleb comprises an initiation phase followed by the expansion and retraction phases.
Blebbing Through the Matrix
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Granulocyte-dependent Autoantibody-induced Skin Blistering
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Breaking the Bubble: Bullous scabies - A case report.

Safi Ur Rehman Daim1, Muhammad Fawad Ashraf1, Aizaz Ashraf2

  • 1Mayo hospital,Anarkali, Lahore 5400, Punjab, Pakistan.

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Bullous scabies, a rare blistering skin condition caused by mites, requires careful diagnosis. Early recognition and treatment with Permethrin cream led to symptom resolution in a case study.

Keywords:
Bullous ScabiesSacroptes scabeiScabiesSkin infection

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Area of Science:

  • Dermatology
  • Parasitology

Background:

  • Scabies is a contagious skin infestation caused by the mite Sarcoptes scabiei.
  • It typically presents with pruritus and papular lesions, transmitted via skin-to-skin contact.

Observation:

  • A 30-year-old female presented with intense pruritus, bullae on hands/feet, and papules.
  • Microscopic examination confirmed Sarcoptes scabiei mites and eggs.

Findings:

  • The patient was diagnosed with bullous scabies, a rare presentation characterized by tense blisters.
  • Treatment with Permethrin cream and antihistamines resulted in symptom regression over two months.

Implications:

  • Bullous scabies should be considered in the differential diagnosis for blistering skin conditions with pruritus.
  • Potential pathophysiology involves Staphylococcus aureus superinfection or autoantibody production.
  • Prompt diagnosis and treatment ensure favorable patient outcomes.