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Polycystic liver diseases: from molecular basis to development of effective treatments
Enara Markaide1, Jesús M Bañales2, Pedro M Rodrigues3
1Liver and Gastrointestinal Diseases, Biodonostia Health Research Institute.
Revista Espanola De Enfermedades Digestivas
|April 28, 2023
Abstract:
Polycystic liver diseases (PLDs) comprise a heterogeneous group of congenital genetic disorders that mainly affect bile duct epithelial cells, known as cholangiocytes. Patients with PLD usually present bile duct dilatation and/or progressive develop intrahepatic, fluid-filled biliary cysts (more than 10), which is the main cause of morbidity.

