COVID-19 infection and seroconversion rates in healthcare workers in Lebanon: An observational study

Mariana Helou1, Sanaa Zoghbi2, Nour El Osta1

  • 1Division of Emergency, Department of Internal Medicine, Lebanese American University, School of Medicine, Beirut, Lebanon.

Medicine
|April 28, 2023
PubMed

Insights

A study found that 19.7% of healthcare workers (HCW) developed severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) antibodies. Seropositivity varied by role, with housekeeping staff showing the highest rates, highlighting the need for better HCW protection.

Area of Science:

  • Infectious Diseases
  • Epidemiology
  • Occupational Health

Background:

  • Coronavirus disease 2019 (COVID-19) poses a significant risk to healthcare workers (HCW).
  • Seroprevalence of severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) varies among HCW populations.
  • Understanding seroconversion rates is crucial for assessing infection risk and implementing protective measures.

Purpose of the Study:

  • To determine the prevalence of SARS-CoV-2 antibodies and seroconversion among HCW in a hospital setting.
  • To identify risk factors associated with seropositivity within different hospital departments.
  • To inform public health policies for HCW protection during the COVID-19 pandemic.

Main Methods:

  • A cross-sectional study involving 203 HCW.
  • Serological testing for SARS-CoV-2 antibodies.
  • Analysis of seroconversion rates and seropositivity by gender and occupational group.

Main Results:

  • Overall seroconversion rate was 19.7%.
  • Seropositivity was higher in males (25%) than females (13.4%).
  • Highest seropositivity rates observed in Housekeeping (83%) and COVID Floor (45%) staff; lowest in Anesthesia (4%) and Infection Control (0%).
  • Prolonged patient contact correlated with higher seropositivity on COVID floors and ICUs.
  • Consistent N95 mask use was associated with lower seropositivity in inhalation and anesthesia teams.

Conclusions:

  • COVID-19 seropositivity among HCW is a significant public health concern.
  • Occupational roles and adherence to protective measures influence infection risk.
  • Enhanced protective policies are necessary to safeguard HCW during pandemics.

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