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Related Experiment Video

Updated: Aug 1, 2025

Ablation of Ischemic Ventricular Tachycardia Using a Multipolar Catheter and 3-dimensional Mapping System for High-density Electro-anatomical Reconstruction
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Multielectrode mapping for premature ventricular contraction ablation - A prospective, multicenter study.

Pedro A Sousa1, Sérgio Barra2, Nuno Cortez-Dias3

  • 1Pacing & Electrophysiology Unit, Cardiology Department, Coimbra's Hospital and University Center, Coimbra, Portugal.

International Journal of Cardiology
|April 28, 2023
PubMed
Summary

Using the PentaRay catheter for premature ventricular contraction (PVC) ablation significantly improved long-term success rates. This advanced mapping technique also reduced procedure times, offering a more effective treatment for ventricular arrhythmias.

Keywords:
Catheter ablationPattern matching filter softwarePentaRay catheterPremature ventricular contraction

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Area of Science:

  • Cardiology
  • Electrophysiology
  • Medical Devices

Background:

  • Premature ventricular contractions (PVCs) are common arrhythmias requiring effective ablation strategies.
  • Current ablation techniques may face challenges in achieving high long-term success rates.
  • Optimizing mapping and ablation procedures is crucial for improving patient outcomes.

Purpose of the Study:

  • To evaluate the efficacy of a multielectrode mapping catheter, specifically the PentaRay catheter, in PVC ablation.
  • To compare the outcomes of PVC ablation using the PentaRay catheter versus standard ablation catheter mapping.
  • To assess the impact of the PentaRay catheter on procedural efficiency and long-term arrhythmia freedom.

Main Methods:

  • A prospective, multicenter nonrandomized study included 136 patients undergoing PVC ablation from January 2018 to June 2021.
  • Patients were divided into two groups: Study Group (PentaRay catheter mapping) and Control Group (ablation catheter mapping).
  • Both groups utilized PMF software, with assessments including procedural endpoints and 1-year freedom from ventricular arrhythmia.

Main Results:

  • The Study Group (PentaRay) acquired significantly more activation points and had shorter mapping and procedure times compared to the Control Group.
  • No significant differences were observed in acute success rates or adverse events between the groups.
  • Patients in the Study Group demonstrated significantly higher 1-year freedom from ventricular arrhythmia (89.7% vs. 70.6%, p=0.01).

Conclusions:

  • The use of the PentaRay catheter is associated with improved long-term outcomes in PVC ablation.
  • This multielectrode mapping catheter may enhance the efficacy of ventricular arrhythmia ablation.
  • The PentaRay catheter offers potential benefits in reducing procedure time while improving success rates.