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Updated: Aug 1, 2025

A Modified Sonographic Algorithm for Image Acquisition in Life-Threatening Emergencies in the Critically Ill Newborn
Published on: April 7, 2023
Critical care among newborns with and without a COVID-19 diagnosis, May 2020-February 2022
Bailey Wallace1, Daniel Chang2,3, Emily O'Malley Olsen2
1Division of Reproductive Health, Centers for Disease Control and Prevention, Atlanta, GA, USA. drhemergencyprep@cdc.gov.
Objective:
To assess COVID-19 association with newborn critical care outcomes, including nursery level of care and ventilation, during three time periods: Pre-delta (May 2020-June 2021), Delta (July-November 2021), and Omicron (December 2021-February 2022).
Study Design:
In a retrospective cohort of newborns born May 2020-February 2022 using the Premier Healthcare Database, we classified COVID-19 status and critical care using International Classification of Diseases 10th Revision and Current Procedural Terminology codes, laboratory data, and billing records and assessed for variation during three time periods.
Results:
Of 1,388,712 newborns, 0.06% had COVID-19 during the birth hospitalization (Pre-delta period: 0.03%; Delta: 0.07%; Omicron: 0.21%). Among newborns with COVID-19, the risks for admission to a higher-level nursery and for invasive or non-invasive ventilation were lower in the Omicron period compared to Pre-delta and Delta periods.
Conclusion:
From May 2020-February 2022, COVID-19 in newborns was rare and cases were less severe during the period of Omicron predominance.
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