Related Experiment Video

Updated: Jun 17, 2026

Applying Stereotactic Injection Technique to Study Genetic Effects on Animal Behaviors
07:54

Applying Stereotactic Injection Technique to Study Genetic Effects on Animal Behaviors

Published on: May 10, 2015

14.3K

Microbiota from young mice counteracts selective age-associated behavioral deficits

Marcus Boehme1,2, Katherine E Guzzetta1,2, Thomaz F S Bastiaanssen1,2

  • 1APC Microbiome Ireland, University College Cork, Cork, Ireland.

Nature Aging
|April 28, 2023
PubMed
Summary

Transplanting gut microbiota from young donors into aged mice improved brain immunity and cognition. This suggests the microbiome could be a therapeutic target for promoting healthy aging.

Area of Science:

  • Microbiology
  • Neuroscience
  • Immunology

More Related Videos

Morris Water Maze Test: Optimization for Mouse Strain and Testing Environment
10:24

Morris Water Maze Test: Optimization for Mouse Strain and Testing Environment

Published on: June 22, 2015

21.6K
Author Spotlight: Understanding Adolescent Social Adversity Effects on Neurodevelopment in Mice
07:15

Author Spotlight: Understanding Adolescent Social Adversity Effects on Neurodevelopment in Mice

Published on: March 15, 2024

1.6K

Related Experiment Videos

Last Updated: Jun 17, 2026

Applying Stereotactic Injection Technique to Study Genetic Effects on Animal Behaviors
07:54

Applying Stereotactic Injection Technique to Study Genetic Effects on Animal Behaviors

Published on: May 10, 2015

14.3K
Morris Water Maze Test: Optimization for Mouse Strain and Testing Environment
10:24

Morris Water Maze Test: Optimization for Mouse Strain and Testing Environment

Published on: June 22, 2015

21.6K
Author Spotlight: Understanding Adolescent Social Adversity Effects on Neurodevelopment in Mice
07:15

Author Spotlight: Understanding Adolescent Social Adversity Effects on Neurodevelopment in Mice

Published on: March 15, 2024

1.6K

Related Concept Videos

Gut-Brain Axis01:22

Gut-Brain Axis

The gut–brain axis is a bidirectional communication system that connects the gastrointestinal tract and the brain. This interaction is mediated through multiple pathways, including the vagus nerve, hormonal signals, immune responses, and chemical messengers produced by gut microbes.Microbial Contributions to Brain FunctionGut microbiota contributes significantly to brain function by producing neuroactive compounds. These include neuroactive compounds that influence neurotransmitters such as...

Articles linked to this work by shared authors, journal, and citation graph.

Generalist Versus Specialist: What Is the Best AI Model for Health Care?

Journal of medical Internet research·2026

How Social Media and Chatbot Bans Could Backfire.

Journal of medical Internet research·2026

Standardised dual-flow cytometry workflows for quantitative assessment of mitochondrial superoxide and mitochondrial mass in live cancer cells and primary multiple myeloma cells.

Frontiers in cell and developmental biology·2026

AI Models Could Improve Diagnosis and Care for Rare Diseases.

Journal of medical Internet research·2026

Lipid metabolism is a key central, systemic and gut microbial feature of the decline in rat hippocampal function during middle age.

Neurobiology of aging·2026

Genetic and enzymatic basis of xylooligosaccharide metabolism by Bifidobacterium longum.

Gut microbes·2026

TNFR1 signaling connects inflammation to impaired fatty acid oxidation to drive intestinal stem cell aging.

Nature aging·2026

Agentic AI for scaling diagnosis and care in neurodegenerative disease.

Nature aging·2026

Plasma proteomics framework predicts metabolic dysfunction-associated steatotic liver disease up to 16 years before onset.

Nature aging·2026

The chemotherapy-induced senescence-associated secretome promotes cell detachment and metastatic dissemination through metabolic reprogramming.

Nature aging·2026

Bioengineering strategies to interrogate and modulate the aging immune system.

Nature aging·2026

Senotypes define the diverse landscape of senescent cells.

Nature aging·2026

Culture-based inventory and functional guild analysis of root-invading fungi associated with grassland plants across multiple regions in China.

Frontiers in plant science·2026

CD22 regulates Aβ clearance in microglia through INPP5D signaling.

Frontiers in cellular neuroscience·2026

The Giardia secretome disrupts gut microbiota biofilms.

Trends in parasitology·2026

Microbial interactions as key players shaping the emergence and spread of de novo resistance mutations.

Microbiology (Reading, England)·2026

Bioprospecting of cultivable actinobacteria from tropical peat swamp forest soil reveals Streptomyces with potent antimicrobial activity.

Antonie van Leeuwenhoek·2026

Description of Sulfitobacter gelatinilyticus sp. nov. and Sulfitobacter weihaiensis sp. nov., isolated from marine sediment.

Antonie van Leeuwenhoek·2026
See all related articles
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies
Jove
Visualize
Contact Us