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Papanicolaou test collection with the Papette brush or the spatula with cytobrush: A pragmatic study
Danielle J O'Laughlin1, Brittany A Strelow1, Nicole A Fellows1
1Division of Community Internal Medicine, Mayo Clinic, Rochester, MN, USA.
Background:
Cotesting with the Papanicolaou (Pap) and human papillomavirus tests detects most precancerous and cancerous lesions and increases the sensitivity for detecting high-grade precancerous and invasive cervical cancers compared with human papillomavirus testing alone.
Objective:
To compare the use of the Papette brush (hereafter Papette) to the traditional spatula with endocervical brush (cytobrush) for cervical cancer screening.
Design:
Pragmatic observational study.
Methods:
Adult women aged 21-64 years who were eligible for a Papanicolaou test at a Midwest Community Internal Medicine practice underwent cervical cancer screening using the Papette or spatula with cytobrush from 18 August 2021 through 1 February 2022. Cluster sampling was used across the practice. Pathology reports were then analyzed to compare the number of satisfactory versus unsatisfactory results between the two collection techniques.
Results:
We collected results for 756 Pap tests. The test results were satisfactory with the Papette 93.8% of the time compared with 93.0% for the spatula with cytobrush.
Conclusion:
The Papette is not inferior to a spatula with cytobrush as a collection method for Pap tests.
