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Updated: Aug 1, 2025

Application of a New Mesh Fixation Method in Laparoscopic Incisional Hernia Repair

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Prophylactic Mesh Placement With Ileal Conduit: A Cost-effectiveness Analysis.

Diboro L Kanabolo¹, Sangtae Park²

¹Department of Urology, University of Washington Medical Center, Seattle, WA.

|April 29, 2023

Summary

This summary is machine-generated.

Prophylactic mesh placement during ileal conduit urinary diversion for bladder cancer is cost-effective. It improves quality of life and prevents parastomal hernias (PSH) across all cancer stages.

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Area of Science:

Urology
Surgical Oncology
Health Economics

Background:

Parastomal hernias (PSH) affect over 50% of stoma patients.
Mesh prophylaxis reduces PSH in end-colostomy and ileal conduits.
Cost-effectiveness of mesh for ileal conduits in bladder cancer is unstudied.

Purpose of the Study:

To evaluate the cost-effectiveness of mesh prophylaxis in ileal conduit urinary diversion for bladder cancer.
To assess the impact of mesh placement on quality of life and PSH prevention.

Main Methods:

A Markov model was developed to analyze costs and quality-adjusted life years (QALY).
Data were sourced from literature and adjusted to 2022 US dollars.
Sensitivity analyses were conducted to validate model robustness.

Main Results:

Mesh placement incurred an average incremental cost of $897.
Mesh provided an average incremental effectiveness of 0.49 QALY.
The incremental cost-effectiveness ratio was $2114.71/QALY.
Mesh benefit was sensitive to infection probability.

Conclusions:

Prophylactic mesh placement is a cost-effective strategy for preventing PSH in bladder cancer patients.
Mesh improves quality of life across all stages of bladder cancer.
Mesh prophylaxis is recommended during radical cystectomy with ileal conduit formation.