Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Concept Videos

Pathophysiology of Diabetes01:20

Pathophysiology of Diabetes

1.0K
Diabetes mellitus is a chronic metabolic disorder characterized by hyperglycemia. The four categories of diabetes are type 1 diabetes, type 2 diabetes, other specific types of diabetes, and gestational diabetes.
Type 1 diabetes is characterized by autoimmune-mediated destruction of pancreatic β cells, with environmental factors potentially triggering this process in genetically susceptible individuals. Despite many not having a family history, certain genes increase susceptibility,...
1.0K
Diabetes Mellitus: Type 2 and Gestational01:22

Diabetes Mellitus: Type 2 and Gestational

2.6K
Type 2 diabetes, characterized by insulin resistance, arises when the insulin receptors on cells lose responsiveness to insulin, diminishing the cell's capacity to take up glucose, resulting in elevated blood glucose levels. To receive a diagnosis of Type 2 diabetes, a series of blood glucose tests are necessary to assess whether the blood glucose falls within normal parameters. If the result is out of the normal range, a patient may be diagnosed as prediabetic or diabetic, depending on the...
2.6K
Hypoglycemia and Glucagon01:15

Hypoglycemia and Glucagon

306
Without prolonged fasting, healthy individuals maintain blood glucose levels above 3.5 mM due to a well-adapted neuroendocrine counterregulatory system that effectively prevents acute hypoglycemia, a potentially life-threatening condition. The primary clinical scenarios for hypoglycemia encompass diabetes treatment, inappropriate production of endogenous insulin or insulin-like substances by tumors, and the use of glucose-lowering agents in non-diabetic individuals. Notably, hypoglycemia in the...
306
SBAR II: Application of SBAR01:14

SBAR II: Application of SBAR

4.5K
SBAR is an effective communication tool used by healthcare professionals to communicate patient information accurately. SBAR stands for Situation, Background, Assessment, and Recommendation. For a better understanding, an example is given below.
SBAR Report from a Nurse to a Health Care Provider
S: "Hello, Dr. Smith. This is Jane, RN, from the Med Surg unit. I am calling to tell you about Ms. White in Room 210, who is experiencing increased pain and redness at her incision site. Her recent...
4.5K
Diabetes Mellitus: Overview and Type I Subtype01:22

Diabetes Mellitus: Overview and Type I Subtype

2.8K
Diabetes mellitus is a chronic metabolic disorder characterized by high blood glucose levels due to inadequate insulin production, insulin resistance, or both. The condition affects millions worldwide and can significantly impact their health and quality of life.
Type 1 diabetes is an autoimmune disease in which the immune system mistakenly attacks and destroys the insulin-producing beta cells in the pancreas. As a result, the body is unable to produce sufficient insulin, and individuals with...
2.8K
Diabetes: Symptoms, Diagnosis, and Complications01:15

Diabetes: Symptoms, Diagnosis, and Complications

613
For most patients, experiencing several weeks of polyuria, polydipsia, fatigue, and significant weight loss may indicate the presence of diabetes. Furthermore, adults displaying the phenotypic appearance of type 2 diabetes (particularly those who are obese and not initially insulin-requiring), may have islet cell autoantibodies, suggesting autoimmune-mediated β cell destruction and a diagnosis of latent autoimmune diabetes of adults (LADA). The categorization of glucose homeostasis is...
613

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by
Same author

Changes in mortality in very preterm neonates in a single institution in Dallas, Texas, 1977-2024: a cohort study.

Pediatric research·2026
Same author

Early Intratracheal Budesonide to Reduce BPD in Extremely Preterm Infants-Reply.

JAMA·2026
Same author

Provider perspectives on counseling and resuscitation at 22 weeks gestation and their impact on decision-making: what do providers think?

Journal of perinatology : official journal of the California Perinatal Association·2026
Same author

Risk factors for subgaleal hemorrhage and adverse early neonatal outcomes: a single-center cohort study with exclusive use of forceps.

Journal of perinatology : official journal of the California Perinatal Association·2025
Same author

Early Intratracheal Budesonide to Reduce Bronchopulmonary Dysplasia in Extremely Preterm Infants: The Budesonide in Babies (BiB) Randomized Clinical Trial.

JAMA·2025
Same author

Ketogenic diet in neonates: effects, pitfalls, and a paradigm from a preterm newborn affected by pyruvate dehydrogenase deficiency.

Journal of perinatology : official journal of the California Perinatal Association·2025

Related Experiment Video

Updated: Aug 1, 2025

Improving IV Insulin Administration in a Community Hospital
12:08

Improving IV Insulin Administration in a Community Hospital

Published on: June 11, 2012

18.9K

Hyperglycemia and prematurity: a narrative review.

Dimitrios Angelis1, Mambarambath A Jaleel2, Luc P Brion2

  • 1Division of Neonatal-Perinatal Medicine, Department of Pediatrics, The University of Texas Southwestern Medical Center, Dallas, TX, USA. dimitrios.angelis@utsouthwestern.edu.

Pediatric Research
|April 29, 2023
PubMed
Summary

Hyperglycemia (high blood sugar) is common in extremely preterm newborns due to immature metabolism. While linked to adverse outcomes, causality and optimal treatment for this condition remain unclear.

More Related Videos

Modeling Encephalopathy of Prematurity Using Prenatal Hypoxia-ischemia with Intra-amniotic Lipopolysaccharide in Rats
07:36

Modeling Encephalopathy of Prematurity Using Prenatal Hypoxia-ischemia with Intra-amniotic Lipopolysaccharide in Rats

Published on: November 20, 2015

11.4K
Characterization of Metabolic Status in Nonhuman Primates with the Intravenous Glucose Tolerance Test
06:59

Characterization of Metabolic Status in Nonhuman Primates with the Intravenous Glucose Tolerance Test

Published on: November 13, 2016

11.0K

Related Experiment Videos

Last Updated: Aug 1, 2025

Improving IV Insulin Administration in a Community Hospital
12:08

Improving IV Insulin Administration in a Community Hospital

Published on: June 11, 2012

18.9K
Modeling Encephalopathy of Prematurity Using Prenatal Hypoxia-ischemia with Intra-amniotic Lipopolysaccharide in Rats
07:36

Modeling Encephalopathy of Prematurity Using Prenatal Hypoxia-ischemia with Intra-amniotic Lipopolysaccharide in Rats

Published on: November 20, 2015

11.4K
Characterization of Metabolic Status in Nonhuman Primates with the Intravenous Glucose Tolerance Test
06:59

Characterization of Metabolic Status in Nonhuman Primates with the Intravenous Glucose Tolerance Test

Published on: November 13, 2016

11.0K

Area of Science:

  • Neonatalogy
  • Endocrinology
  • Biochemistry

Background:

  • Hyperglycemia is frequently observed in extremely preterm infants.
  • Physiological causes include immaturity of glucose metabolism pathways.
  • Existing research lacks definitive evidence for causality between hyperglycemia and adverse outcomes.

Purpose of the Study:

  • To review the relationship between hyperglycemia and organ development in preterm newborns.
  • To explore the association between hyperglycemia and immediate/long-term outcomes.
  • To discuss current treatment options and identify knowledge gaps.

Main Methods:

  • Literature review of studies on hyperglycemia in extremely preterm newborns.
  • Analysis of data on organ development and clinical outcomes.
  • Synthesis of information on treatment strategies and research needs.

Main Results:

  • Hyperglycemia is common and less understood than hypoglycemia in this population.
  • Immature cellular pathways contribute to glucose dysregulation.
  • Observed associations with adverse outcomes require further investigation for causality.

Conclusions:

  • Understanding hyperglycemia in preterm infants is complicated by varying definitions and treatments.
  • Further research is needed to establish causality and optimize management.
  • Clarifying the impact of hyperglycemia on development and outcomes is crucial.