Related Experiment Video
Updated: Aug 1, 2025
08:08
Chicken Recombinant Limbs Assay to Understand Morphogenesis, Patterning, and Early Steps in Cell Differentiation
Published on: January 12, 2022
2.3K
Introduction to Limb Deficiency for the Pediatrician
1Division of Pediatric Rehabilitation, Department of Orthopedics, Rady Children's Hospital, University of California - San Diego, 3020 Children's Way, MC5096, San Diego, CA 92123-4223, USA.
Pediatric Clinics of North America
|April 30, 2023
Summary
Pediatricians play a crucial role in managing limb deficiencies due to a shortage of specialized professionals. This guide covers causes, diagnosis, surgical options, prosthetic care, and resources for children with limb differences.
Area of Science:
- Pediatric Medicine
- Orthopedics
- Rehabilitation Medicine
Background:
- Limited availability of trained amputee care professionals necessitates pediatrician involvement.
- Children with limb deficiencies require comprehensive management strategies.
Purpose of the Study:
- To provide pediatricians with essential knowledge for managing children with limb deficiencies.
- To outline diagnostic, surgical, and prosthetic care considerations.
- To offer resources for clinicians and families.
Main Methods:
- Literature review on causes, epidemiology, and management of limb deficiencies.
- Discussion of evaluation, diagnostic workup, and surgical interventions.
- Overview of prosthetic prescription, care, and rehabilitation.
Main Results:
- Identified common causes and epidemiological factors of limb deficiency.
- Detailed evaluation and diagnostic approaches.
- Provided guidance on surgical considerations and prosthetic management.
- Reviewed associated overuse syndromes and mental health challenges.
- Compiled resources for funding, support, and education.
Conclusions:
- Pediatricians are vital in the care of children with limb deficiencies.
- A multidisciplinary approach is essential for optimal outcomes.
- Access to resources and education is critical for effective management and family support.
Related Concept Videos
01:07Development of the Limb Synovial Joints
1.4K
Joints form during embryonic development in conjunction with the formation and growth of the associated bones. The embryonic tissue that gives rise to all bones, cartilage, and connective tissues of the body is called mesenchyme.
The mesenchymal stem cells differentiate into chondrocytes that form the hyaline cartilage, and later the cartilaginous model of the bone. This model further transforms into a bone. This process is known as endochondral ossification.
During development, the limbs...
The mesenchymal stem cells differentiate into chondrocytes that form the hyaline cartilage, and later the cartilaginous model of the bone. This model further transforms into a bone. This process is known as endochondral ossification.
During development, the limbs...
1.4K
01:21Peripheral Arterial Disease II: Clinical Manifestations and Diagnostic Evaluation
20
Clinical manifestationsPeripheral Arterial Disease (PAD) manifests through a range of symptoms, from the characteristic intermittent claudication to atypical presentations and severe complications in advanced stages. Intermittent claudication, a hallmark symptom of PAD, presents as exercise-induced muscle pain that typically resolves within minutes of rest. This pain is reproducible and stems from inadequate blood flow, leading to the accumulation of lactic acid produced during anaerobic...
20
01:09Changes in the Appendicular Skeleton with Age
2.1K
The upper and lower limb initially develops as a small bulge called a limb bud, which appears on the lateral side of the early embryo. The upper limb bud appears near the end of the fourth week of development, with the lower limb bud appearing shortly after.
Initially, the limb buds consist of a core of mesenchyme covered by a layer of ectoderm. The ectoderm at the end of the limb bud thickens to form a narrow crest called the apical ectodermal ridge. This ridge stimulates the underlying...
Initially, the limb buds consist of a core of mesenchyme covered by a layer of ectoderm. The ectoderm at the end of the limb bud thickens to form a narrow crest called the apical ectodermal ridge. This ridge stimulates the underlying...
2.1K
01:30Peripheral Artery Disease I: Introduction
12
Peripheral artery disease (PAD) predominantly results from atherosclerosis, which involves the accumulation of fatty deposits, or plaques, within the walls of arteries. This causes them to narrow and harden, significantly reducing blood flow. PAD predominantly affects the legs but also impacts other areas, such as the arms, thereby impairing overall circulation and organ function.Etiology of PAD:The principal cause of PAD is atherosclerosis, which results from fatty deposits inside the arterial...
12
01:20Introduction to the Skeletal System
5.9K
The skeletal system is the central framework of the body, consisting of different connective tissues: bones, cartilage, tendons, and ligaments.
Components of the Skeletal System
Bone, or osseous tissue, is a hard connective tissue that forms an internal support structure for the human body. Bones shield vulnerable organs and soft tissue from external forces. For example, the vertebral bones protect and support the spinal cord.
Cartilage, a semi-rigid connective tissue found in regions such as...
Components of the Skeletal System
Bone, or osseous tissue, is a hard connective tissue that forms an internal support structure for the human body. Bones shield vulnerable organs and soft tissue from external forces. For example, the vertebral bones protect and support the spinal cord.
Cartilage, a semi-rigid connective tissue found in regions such as...
5.9K
01:29Bone Disorders
3.7K
Aging and its effect on bone remodeling is the most common cause of bone disorders. In young and healthy people, bone deposition and resorption happen at an equal rate to maintain optimal bone health.
Bone deposition is also affected by the levels of sex hormones like estrogen and testosterone that promote osteoblast activity and bone matrix synthesis. When the level of these hormones decreases due to aging, it causes a reduction in bone deposition. As a result, bone resorption by osteoclasts...
Bone deposition is also affected by the levels of sex hormones like estrogen and testosterone that promote osteoblast activity and bone matrix synthesis. When the level of these hormones decreases due to aging, it causes a reduction in bone deposition. As a result, bone resorption by osteoclasts...
3.7K