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Disseminated peritoneal leiomyomatosis: A case report
Zineb Izi1, Mustapha Outznit1, Amine Cherraqi1
1Department of Radiology, Ibn Sina University Hospital, University Mohammed V Morocco, Rabat, Morocco.
Radiology Case Reports
|May 1, 2023
Summary
Disseminated peritoneal leiomyomatosis (DPL) is a rare benign condition causing smooth muscle nodules in the abdomen. Imaging aids diagnosis, and malignant transformation risk is low, as seen in a post-hysterectomy case.
Area of Science:
- Gynecologic Pathology
- Abdominal Imaging
- Surgical Oncology
Background:
- Disseminated peritoneal leiomyomatosis (DPL) is a rare, benign condition characterized by smooth muscle nodules throughout the abdominopelvic cavity.
- The etiology is unclear, with suspected links to iatrogenic factors or hormonal stimulation, primarily affecting women of reproductive age.
Observation:
- A 41-year-old woman presented with numerous peritoneal tumors four years after a laparoscopic hysterectomy.
- Computed tomography (CT) and magnetic resonance imaging (MRI) suggested DPL.
- Histological examination confirmed the diagnosis of DPL.
Findings:
- DPL presents as multiple solid peritoneal smooth muscle nodules.
- Imaging modalities like CT and MRI are crucial for assessing lesion extent and evaluating for malignancy.
- Histopathology is essential for definitive diagnosis.
Implications:
- This case highlights DPL as a differential diagnosis in women with peritoneal nodules, particularly post-gynecologic surgery.
- While DPL is benign with a low risk of malignant transformation, thorough diagnostic workup is necessary.
- Further research into DPL's pathogenesis and standardized management strategies is warranted.
