The Clot Thickens: COVID-19-Related ST-Elevation Myocardial Infarction in the Setting of Recent Boosters

Amar R Patel1, Kunal Mishra2, Andrew J Ortega3

  • 1Internal Medicine, Texas Tech University Health Sciences Center El Paso, El Paso, USA.

Cureus
|May 1, 2023
PubMed

Insights

This case report details a COVID-19 patient who experienced ST-elevated myocardial infarction (STEMI) after a booster vaccine. It highlights the complex thrombotic risks from combined COVID-19 infection and vaccination.

Area of Science:

  • Cardiology
  • Infectious Diseases
  • Vaccinology

Background:

  • Coronavirus disease 2019 (COVID-19) presents diverse pathological effects.
  • COVID-19 vaccines are primary tools, but their thrombotic risks, especially combined with infection, require further study.
  • ST-elevated myocardial infarction (STEMI) is a serious cardiac event.

Observation:

  • A patient with recent COVID-19 diagnosis received a booster vaccination.
  • The patient subsequently developed STEMI.
  • This case explores the thrombotic burden in a COVID-19-associated STEMI scenario.

Findings:

  • The case illustrates a potential cumulative pro-thrombotic effect.
  • This effect may arise from concomitant symptomatic COVID-19 infection and a recent COVID-19 booster.
  • Treatment outcomes for COVID-19-associated clots were reviewed.

Implications:

  • Understanding the complex interplay between COVID-19 infection, vaccination, and thrombotic events like STEMI is crucial.
  • This case emphasizes the need for vigilance regarding cardiovascular risks in patients with recent COVID-19 and vaccination.
  • Further research is warranted to establish the definitive thrombotic risks associated with combined COVID-19 infection and vaccination.

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