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Updated: Jul 31, 2025

Drug-Induced Sleep Endoscopy DISE with Target Controlled Infusion TCI and Bispectral Analysis in Obstructive Sleep Apnea
Published on: December 6, 2016
The Effect of Tonsillectomy and Adenoidectomy on Upper Airway Obstruction Patterns in Children with Obstructive Sleep
Kelsey Mothersole1, Seckin Omer Ulualp1,2, Peter Szmuk3,4,5
1Department of Otolaryngology-Head and Neck Surgery, University of Texas Southwestern Medical Center, Dallas, TX, United States.
Insights
Tonsillectomy and adenoidectomy (TA) in children with obstructive sleep apnea (OSA) often show persistent upper airway obstruction. Drug-induced sleep endoscopy (DISE) helps identify these persistent obstruction sites after TA surgery.
Area of Science:
- Otolaryngology
- Pediatric Sleep Medicine
- Respiratory Physiology
Background:
- Obstructive sleep apnea (OSA) in children is frequently treated with tonsillectomy and adenoidectomy (TA).
- Understanding post-operative airway dynamics is crucial for managing residual OSA.
- Drug-induced sleep endoscopy (DISE) is a tool to assess airway obstruction during sleep.
Purpose of the Study:
- To evaluate the impact of TA on upper airway obstruction patterns using DISE.
- To identify changes in the location and degree of airway obstruction after TA.
Main Methods:
- Retrospective review of medical records for 27 pediatric patients (aged 2-18) with OSA.
- Comparison of DISE findings before and immediately after TA surgery.
- Analysis of obstruction at velum, oropharynx/lateral walls, tongue, and epiglottis levels.
Main Results:
- All patients exhibited multi-level upper airway obstruction pre-TA.
- Post-TA, obstruction decreased significantly at the velum and oropharynx/lateral walls.
- Obstruction persisted in most patients at multiple sites, including the velum and oropharynx.
Conclusions:
- TA surgery may not resolve all upper airway obstruction sites in children with multi-level OSA.
- DISE findings pre-TA can indicate persistent obstruction post-surgery.
- Further research is needed to validate DISE in predicting residual OSA and guiding post-TA management.
Abstract:
Introduction Alterations in upper airway flow dynamics and sites of airway obstruction immediately after tonsillectomy and adenoidectomy (TA) have not been assessed. Identification of the changes in airway obstruction patterns after TA potentially improves the surgical management of children with obstructive sleep apnea (OSA). Objective To evaluate the effect of TA on upper airway obstruction patterns detected with drug-induced sleep endoscopy (DISE). Methods The medical records of patients who underwent pre-TA DISE during the induction of anesthesia and post-TA DISE at the end of TA were reviewed. Data pertaining to polysomnography and DISE findings were analyzed. Results Twenty-seven patients (15 male and 12 females aged between 2 and 18 years old) were identified. All patients had obstruction at multiple sites of the upper airway. Prior to TA, airway obstruction was at the level of the velum in 27 patients, of the oropharynx/lateral walls in 27, of the tongue in 7, and of the epiglottis in 4. After TA, airway obstruction was at the level of the velum in 24 patients, of the oropharynx/lateral walls in 16, of the tongue in 6, and of the epiglottis in 4. The degree of obstruction at the levels of the velum and oropharynx/lateral walls after TA was significantly decreased. Conclusions Drug-induced sleep endoscopy performed prior to TA revealed that most of the sites of airway obstruction persisted after TA in OSA children with multiple sites of airway obstruction. Further studies in larger group of children with OSA are needed to establish the value of DISE findings in predicting residual OSA after TA, surgical planning, determining the need for post TA sleep study, and counseling caregivers.
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