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A previously unreported case of suppurative thrombophlebitis due to Clavispora lusitaniae
Toru Yoneda1, Takayuki Hoshina1, Tomofumi Fukuda1
1Department of Pediatrics, School of Medicine, University of Occupational and Environmental Health, Japan, Kitakyushu, Fukuoka, Japan.
Abstract:
We report a case with Clavispora lusitaniae-induced purulent thrombophlebitis. The patient had multiple risk factors for the development of fungal thrombophlebitis including surgical procedure, mechanical ventilation, admission to intensive care unit, total parenteral nutrition and long-term antimicrobial therapy in addition to the insertion of central venous catheter. The symptoms finally improved by a combination therapy of micafungin and flucytosine, but the therapy did not rapidly resolve candidemia. The appropriate antifungal therapy for C. lusitaniae-induced purulent thrombophlebitis is uncertain. Further study is desired to seek the appropriate therapy for the disease.
Insights
This case study details Clavispora lusitaniae causing purulent thrombophlebitis in a patient with multiple risk factors. Combination antifungal therapy showed improvement but did not fully resolve candidemia, highlighting the need for optimal treatment strategies.
Area of Science:
- Medical Mycology
- Infectious Diseases
- Clinical Case Reports
Background:
- Fungal thrombophlebitis is a serious complication, particularly in critically ill patients.
- Clavispora lusitaniae is an emerging fungal pathogen that can cause invasive infections.
- Identifying risk factors and effective treatments for fungal thrombophlebitis is crucial.
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