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Intraventricular ganglioglioma: a rare case report
Constantinos Thoma1, Gráinne McKenna2
1Barts & The London School of Medicine & Dentistry, London E1 2AD, UK.
Journal of Surgical Case Reports
|May 2, 2023
Summary
A rare brain tumor, ganglioglioma, was found in the lateral ventricle of a young male. This World Health Organization Grade 1 tumor presented with symptoms like headache and vomiting.
Area of Science:
- Neuro-oncology
- Neuropathology
- Neurosurgery
Background:
- Gangliogliomas are rare central nervous system tumors comprising neuronal and glial elements.
- Intraventricular gangliogliomas are exceptionally uncommon, with few documented cases.
- Understanding their presentation and characteristics is crucial for diagnosis and management.
Observation:
- A 23-year-old male presented with acute headache and vomiting.
- Brain imaging revealed a calcified, enhancing lesion in the trigone of the right lateral ventricle.
- The lesion caused entrapment of the temporal horn and showed signs of recent hemorrhage during surgery.
Findings:
- Histopathological and immunohistochemical analyses confirmed a ganglioglioma.
- The tumor exhibited World Health Organization (WHO) Grade 1 characteristics, indicating a low-grade malignancy.
- Surgical findings included a hemorrhagic and friable lesion.
Implications:
- This case highlights the importance of considering rare intraventricular tumors in the differential diagnosis of neurological symptoms.
- The findings contribute to the limited literature on intraventricular gangliogliomas, particularly their imaging and pathological features.
- Further research into the specific behavior and treatment of intraventricular gangliogliomas may be warranted.
