Catecholamine Mega Storm Triggered by Cocaine Use and Thyrotoxicosis Crisis
Al Ameen Oredegbe1, Mina Awad1
1Internal Medicine, Albany Medical Center, Albany, USA.
Cureus
|May 2, 2023
Summary
Takotsubo cardiomyopathy (TCM) can be triggered by thyroid storm and cocaine abuse. Prompt treatment of thyroid storm led to full recovery of heart function in a patient with Graves
Area of Science:
- Cardiology
- Endocrinology
Background:
- Takotsubo cardiomyopathy (TCM) is a reversible heart condition often triggered by stress.
- Thyroid storm and cocaine use are known potential triggers for TCM.
- Graves' disease is an autoimmune disorder causing hyperthyroidism, which can lead to thyroid storm.
Observation:
- A 26-year-old male with Graves' disease and a history of cocaine abuse presented with thyroid storm.
- The patient developed takotsubo cardiomyopathy and cardiogenic shock secondary to the thyroid storm.
- He required advanced life support, including extracorporeal membrane oxygenation (ECMO).
Findings:
- Treatment of the thyroid storm with antithyroid medications and steroids was initiated.
- The patient showed complete recovery of left ventricular function.
- He was successfully weaned from mechanical circulatory support and vasopressors.
Implications:
- This case highlights the critical link between thyroid storm, substance abuse, and TCM.
- Aggressive management of the underlying thyroid storm is crucial for cardiac recovery in such cases.
- Early recognition and comprehensive treatment, including advanced support, can lead to favorable outcomes in severe TCM.
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