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Stability and Inactivation of Monkeypox Virus on Inanimate Surfaces.

Toni Luise Meister1, Yannick Brüggemann1, Daniel Todt1,2

  • 1Department for Molecular and Medical Virology, Ruhr University Bochum, Bochum.

The Journal of Infectious Diseases
|May 2, 2023
PubMed
Summary
This summary is machine-generated.

Monkeypox virus (MPXV) remains stable on surfaces, especially at lower temperatures. Alcohol-based disinfectants effectively inactivate MPXV, supporting their use for hygiene and outbreak control.

Keywords:
MPXVdisinfectioninactivationinanimate surfacestability

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Area of Science:

  • Virology
  • Infectious Diseases
  • Public Health

Background:

  • Non-zoonotic monkeypox virus (MPXV) spread highlights the need for updated hygiene protocols.
  • Limited data exist on MPXV's stability on environmental surfaces.

Purpose of the Study:

  • To assess the stability of infectious MPXV on stainless steel under various conditions.
  • To determine the efficacy of common disinfectants against MPXV on surfaces.

Main Methods:

  • MPXV stability was tested on stainless steel at different temperatures.
  • Interfering substances were used to simulate environmental contamination.
  • Inactivation efficacy of alcohol- and aldehyde-based disinfectants was evaluated.

Main Results:

  • MPXV persistence on surfaces increased as temperature decreased.
  • MPXV was efficiently inactivated by alcohol- and aldehyde-based disinfectants.
  • The virus demonstrated significant stability on inanimate surfaces.

Conclusions:

  • MPXV exhibits notable stability on inanimate surfaces, particularly at lower temperatures.
  • Alcohol-based disinfectants are effective for MPXV inactivation.
  • Findings support the use of alcohol-based disinfectants for prevention and outbreak management.