Related Experiment Video
Updated: Jul 31, 2025

A Novel Approach for the Administration of Medications and Fluids in Emergency Scenarios and Settings
Published on: November 9, 2016
Risks and benefits of urinary catheterisation during inpatient diuretic therapy for acute heart failure: a
Gregor John1,2,3, Marc Arcens3, Gregory Berra3
1Department of Medicine, Université de Genève, Geneva, Switzerland gregor.john@rhne.ch.
Insights
Urinary catheterisation (UC) in acute congestive heart failure patients did not improve weight loss during diuretic therapy. UC increased urinary tract infection (UTI) risk without offering clinical benefits, suggesting it should not be systematically used.
Area of Science:
- Cardiology
- Nephrology
- Infectious Diseases
Background:
- Patients with acute congestive heart failure (HF) often receive urinary catheterisation (UC) upon hospital admission.
- The clinical utility and potential risks of UC in this population remain subjects of investigation.
Purpose of the Study:
- To evaluate the clinical benefits of UC regarding weight loss in acute congestive HF patients undergoing diuretic therapy.
- To assess the impact of UC on the risk of urinary tract infection (UTI) and other clinical outcomes.
Main Methods:
- A retrospective, non-inferiority study compared 113 catheterised HF patients with 346 non-catheterised patients within 24 hours of diuretic therapy.
- Primary endpoint: weight loss at 48 hours. Secondary endpoints: time to target weight, diuretic discontinuation, respiratory failure resolution, UTI, readmission, and mortality.
Main Results:
- Weight loss at 48 hours was not statistically different between groups (adjusted difference: 0.43 kg, favoring UC, p<0.01 for non-inferiority).
- UC did not significantly impact time to target weight, diuretic discontinuation, or respiratory failure resolution.
- UC significantly increased UTI risk (aHR 2.5) but showed no association with readmission or 1-year mortality.
Conclusions:
- Urinary catheterisation within 24 hours of initiating diuretic treatment for acute congestive HF offers no significant clinical benefit in terms of weight loss or clinical improvement.
- UC is associated with an increased risk of urinary tract infections.
- The findings argue against the routine, systematic use of urinary catheterisation in patients with acute congestive heart failure receiving diuretic therapy.
Objectives:
Patients with acute congestive heart failure (HF) regularly undergo urinary catheterisation (UC) at hospital admission. We hypothesised that UC has no clinical benefits with regard to weight loss during inpatient diuretic therapy for acute congestive HF and increases the risk of urinary tract infection (UTI).
Design:
Retrospective, non-inferiority study.
Setting:
Geneva University Hospitals' Department of Medicine, a tertiary centre.
Participants:
In a cohort of HF patients, those catheterised within 24 hours of diuretic therapy (n=113) were compared with non-catheterised patients (n=346).
Primary And Secondary Outcome Measures:
The primary endpoint was weight loss 48 hours after starting diuretic therapy. Secondary endpoints were time needed to reach target weight, discontinuation of intravenous diuretics and resolution of respiratory failure. Complications included the time to a first UTI, first hospital readmission and death.
Results:
A total of 48-hour weight loss was not statistically different between groups and the adjusted difference was below the non-inferiority boundary of 1 kg (0.43 kg (95% CI: -0.03 to 0.88) in favour of UC, p<0.01 for non-inferiority). UC was not associated with time to reaching target weight (adjusted HR 1.0; 95% CI: 0.7 to 1.5), discontinuation of intravenous diuretics (aHR 0.9; 95% CI: 0.7 to 1.2) or resolution of respiratory failure (aHR 1.1; 95% CI: 0.5 to 2.4). UC increased the risk of UTI (aHR 2.5; 95% CI: 1.5 to 4.2) but was not associated with hospital readmission (aHR 1.1; 95% CI: 0.8 to 1.4) or 1-year mortality (aHR 1.4; 95% CI: 1.0 to 2.1).
Conclusion:
In this retrospective study, with no obvious hourly diuresis-based diuretic adjustment strategy, weight loss without UC was not inferior to weight loss after UC within 24 hours of initiating diuretic treatment. UC had no impact on clinical improvement and increased the risk of UTI. This evidence, therefore, argues against the systematic use of UC during a diuretic therapy for HF.
More Related Videos
Related Concept Videos
Cardiac Catheterization I: Pre-Procedure Overview
Cardiac Catheterization IV: Nursing Management
Heart Failure Drugs: Diuretics
Acute Kidney Injury IV: Diagnostic Studies and Prevention
Heart Failure V: Medical Management
Acute Kidney Injury V: Interprofessional Care

