Reduction of double chin without surgery using ascorbic acid and ascorbyl-palmitate solution: a clinical study

Area of Science:

• Dermatology
• Aesthetic Medicine
• Cosmetic Science

Background:

• Submental fat, commonly known as a double chin, is a prevalent aesthetic concern.
• Existing treatments for double chin include surgical procedures and minimally invasive techniques.
• There is a continuous need for effective and well-tolerated non-surgical treatments for submental fat reduction.

Purpose of the Study:

• To evaluate the efficacy of a new lipolytic solution for treating double chin.
• The solution contains sodium ascorbate (0.24%) and ascorbyl-palmitate (0.020%) as a surfactant agent.

Main Methods:

• A clinical study involving 10 healthy adult subjects (8 female, 2 male) with double chin.
• Subjects received 4 treatment sessions over 8 weeks (biweekly).
• No other active agents were used concurrently.

Main Results:

• A reduction in chin convexity was observed in all subjects post-treatment.
• 90% (9 out of 10) of patients showed improvement in submental appearance.
• One patient did not experience improvement and discontinued treatment.

Conclusions:

• The tested adipocytolytic solution, a mixture of sodium ascorbate and ascorbyl-palmitate, proved successful in treating double chin.
• The formulation demonstrates potential as a novel treatment for submental fat.
• Further research may explore long-term effects and optimal application protocols.