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Bioinformatics Resources for the Study of Glycan-Mediated Protein Interactions
Published on: January 20, 2022
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Bridging glycoinformatics and cheminformatics: integration efforts between GlyCosmos and PubChem
Tiejun Cheng1, Tamiko Ono2, Masaaki Shiota2
1National Center for Biotechnology Information, National Library of Medicine, National Institutes of Health, Bethesda, MD 20894, United States.
Glycobiology
|May 2, 2023
Summary
GlyCosmos and PubChem now integrate glycoscience and chemistry data. This enhances access to glycan structures, genes, diseases, and pathways for researchers.
Area of Science:
- Glycoscience
- Cheminformatics
- Bioinformatics
Background:
- GlyCosmos is a major portal for glycoscience data, including glycans, genes, and pathways.
- PubChem is a comprehensive chemistry portal with data on chemicals, genes, and bioassays.
Purpose of the Study:
- To integrate complementary data from GlyCosmos and PubChem.
- To enable cross-domain data access between glycoscience and chemistry resources.
- To improve user access to glycan-related information.
Main Methods:
- Integration of glycan structures, genes, diseases, glycoproteins, and pathways.
- Cross-linking of related information between the two portals.
- Development of user-friendly interfaces for data access and reuse.
Main Results:
- Successful integration of data from GlyCosmos and PubChem.
- Enhanced cross-referencing between glycan and chemical information.
- Improved data discoverability and accessibility for life science researchers.
Conclusions:
- The integration provides enhanced access to glycan-related information.
- Researchers benefit from improved awareness and data reuse across domains.
- This collaboration bridges glycoscience and chemistry data resources effectively.
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