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Updated: Jul 31, 2025

A Melanoma Patient-Derived Xenograft Model
Published on: May 20, 2019
[Surgery for malignant melanoma - Expected standards]
Zsolt Kádár1, Zsuzsanna Lengyel1, Rolland Gyulai1
1Pécsi Tudományegyetem, Klinikai Központ, Bőr-, Nemikórtani és Onkodermatológiai Klinika, Pécs, Magyarország.
Abstract:
Melanoma surgery has changed significantly in recent years. The highly radical operations with many complications, in addition to which the complete and disease-free survival remained low, were gradually replaced by less radical operations. With the introduction of new systemic treatments (targeted and immuno-oncological) in adjuvant indications, certain surgeries, such as elective block dissections, have now been displaced from surgical treatments and the role of surgery has also been re-evaluated. The surgery for primary tumor removal, reexcision, sentinel lymph node biopsy and lymph region surgery, and surgical treatment of skin and distant metastases have changed. In this summary communication, the authors provide an overview of the currently accepted surgical therapy of melanoma malignum based on the international literature and their own practice.

