Related Experiment Video
Updated: Jul 31, 2025

Mouse Model of Surgical Uterine Injury and Subsequent Pregnancy Outcomes
Published on: June 27, 2025
Placenta Accreta Spectrum and Postpartum Hemorrhage.
Mahmoud Abdelwahab1, Michael Cackovic
1Department of Obstetrics and Gynecology, The Ohio State University College of Medicine, Columbus, Ohio.
Placenta accreta spectrum involves abnormal placental invasion into the uterine wall, posing significant maternal health risks. Early diagnosis via imaging and timely management, often involving hysterectomy, are crucial for patient outcomes.
Area of Science:
- Obstetrics and Gynecology
- Maternal-Fetal Medicine
Background:
- Placenta accreta spectrum (PAS) is characterized by abnormal trophoblastic invasion into the uterine wall.
- PAS is a leading cause of severe maternal morbidity and mortality.
- The incidence of PAS has risen, linked to increased cesarean delivery rates.
Purpose of the Study:
- To summarize the key aspects of placenta accreta spectrum.
- To highlight diagnostic modalities and management strategies for PAS.
Main Methods:
- Review of existing literature on placenta accreta spectrum.
- Synthesis of information regarding diagnosis and management.
Main Results:
- PAS severity ranges from superficial invasion to deep myometrial and serosal penetration (percreta).
- Ultrasound is the primary diagnostic tool, with MRI used for detailed assessment.
- Hysterectomy at delivery is a common management approach, with alternatives like delayed hysterectomy or expectant management.
Conclusions:
- Placenta accreta spectrum requires careful diagnosis and management planning.
- Management strategies should be tailored to individual patient cases and severity of invasion.
More Related Videos
09:52Accurate and Simple Evaluation of Vascular Anastomoses in Monochorionic Placenta using Colored Dye
Published on: September 5, 2011
05:31Author Spotlight: Modeling an Aspect of Preeclampsia in Female Mice Using Hypoxic Human Placenta-Derived Small Extracellular Vesicles
Published on: January 26, 2024
Related Concept Videos
Pathophysiology of Diabetes
Type 1 diabetes is characterized by autoimmune-mediated destruction of pancreatic β cells, with environmental factors potentially triggering this process in genetically susceptible individuals. Despite many not having a family history, certain genes increase susceptibility,...
Disorders of Hemostasis
Thromboembolic Disorders
Two factors primarily cause thromboembolic conditions.
Peripheral Artery Disease V: Postoperative Nursing Management
Pulmonary Embolism II: Diagnostic Studies and Interprofessional Care
Fetal Circulation
Two umbilical arteries transport blood from the fetus to the placenta. At the placenta, the blood absorbs oxygen and nutrients while simultaneously eliminating waste products. This oxygen-enriched and nutrient-rich blood then returns to the fetus through one...
Teratogenicity